Guanidine compounds have important biochemical properties. Aminoguanidine, as an example, is an anti-oxidant, a nitric oxide synthase inhibitor (NOS) which prevents nitric oxide formation, and an inhibitor of advanced glycosylation end products (AGEs). As an anti-oxidant, aminoguanidine may affect the formation of atherosclerotic lesions through protection from LDL oxidation. Inhibition of AGEs...

As long as health communications have existed in the USA, Americans have faced the task of sorting the agenda of the source from the advice it provides. That task has become more complicated as advances in the science of nutrition and the technology used to present it have heightened the complexity of nutrition communications. Getting consumers to adopt a healthier diet has been a protracted un...

ITE JOURNAL / JANUARY 2003 INTRODUCTION Approaches to combat urban traffic congestion span from demand management to physical expansion of road capacity. Attempts to shift a part of peak travel from car to high-quality public transit and to times when roads are relatively less crowded sometimes have been successful.1,2 Also, intelligent transportation systems (ITS) have the promise to optimize ...

Crusted scabies is the most severe presentation of infection related to the bite of the mite Sarcoptes scabiei var hominis. It is usually seen in patients with an underlying immunosuppressive condition. Case reports and studies suggest that infection with human T-cell lymphotropic virus 1 (HTLV-1) is a major predisposing factor to S scabiei infestation. This case report describes severe crusted...

9. De Moraes, C. M., Lewis, W. J., Paré, P. W., Alborn, H. T. & Tumlinson, J. H. Nature 393, 570–573 (1998). 10.Du, Y. et al. J. Chem. Ecol. 22, 1591–1606 (1996). single person’s IQ-test performance (assuming a test reliability of 0.95, the 50% confidence interval would be 4.5 IQ points wide). To account for the Mozart effect, Rauscher’s group appealed to a model of cortical computation whose o...

The role of vitamin status in the development of the brain and the subsequent functioning of the brain was considered. There are data with a range of vitamins, from animal studies and human studies in developing countries, suggesting that a clinical deficiency during the critical period when the brain is developing causes permanent damage. To date there is, however, with the exception of cases ...

For many years there was little discussion of or activity to develop new energetic materials for military applications. However, since the end of the Cold War there have been significant new activities in such materials. Particularly in the last 10 years, a number of new synthesized energetic materials have been reported and generated much discussion. Some of the most interesting newly develope...

The epidermis is highly sensitive to retinoids, and vitamin A (retinol) is a critical factor in the regulation of skin cell differentiation and proliferation. Despite extensive knowledge of retinoid-mediated gene transcription effects on epidermal cells and evidence for retinoid-mediated suppression of carcinogenesis in skin, basic transport events, especially cellular uptake, of this vitamin r...

Marcello Disertori ([email protected]) Maria Grazia Franzosi ([email protected]) Simona Barlera ([email protected]) Franco Cosmi ([email protected]) Silvia Quintarelli ([email protected]) Chiara Favero ([email protected]) Glauco Cappellini ([email protected]) Gianna Fabbri ([email protected]) Aldo Pietro Magg...