نتایج جستجو برای: whole genome sequencing
تعداد نتایج: 563390 فیلتر نتایج به سال:
26 Drug-resistance to tuberculosis remains a major public health threat. Here, we report two cases 27 of extended-spectrum XDR (XXDR) tuberculosis, resistant to most first and second-line agents. 28 Correlation of whole-genome sequencing (WGS) and phenotypic testing was discordant, 29 suggesting over-reliance on WGS may miss clinically relevant resistance in extensively drug30 resistant disease...
M 858.888.7600 F 858.888.7601 | [email protected] | bionanogenomics.com © Copyright 2017, Bionano Genomics Inc. For research use only. Not for use in diagnostic procedures. 1 Existing technologies including chromosomal microarrays and whole genome sequencing diagnose less than 50% of patients with genetic disorders. This leaves a majority of patients without ever receiving a molecular di...
PURPOSE OF REVIEW Comparative genome sequencing studies of human fungal pathogens enable identification of genes and variants associated with virulence and drug resistance. This review describes current approaches, resources, and advances in applying whole genome sequencing to study clinically important fungal pathogens. RECENT FINDINGS Genomes for some important fungal pathogens were only re...
There is increasing evidence that several genes are associated with an increased risk of type 2 diabetes (T2D); genome-wide association investigations and whole-genome re‑sequencing investigations offer a useful approach for the identification of genes involved in common human diseases. To further investigate which polymorphisms confer susceptibility to T2D, the present study screened for high‑...
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