The study investigated differences in the Five-Factor Model (FFM) domains and facets across adulthood. The main questions were whether personality scales reflected coherent units of trait development and thereby coherent personality traits more generally. These questions were addressed by testing if the components of the trait scales (items for facet scales and facets for domain scales) showed ...

a-Neo-endorphin anddynorphin immunoreactivities in rat brain were visualized by double antibody immunofluorescence of frozen sections. Antibodies were used that were specific for their respective antigens. The pattern of neuronal immunostaining produced by a-neo-endorphin and dynorphin antisera in adjacent serial sections was completely superimposible. No areas were found in which a-neo-endorph...

This article explores some concerns about the concept of neo-liberalism, suggesting that it has been stretched too far to be productive as a critical analytical tool. Neo-liberalism suffers from promiscuity (hanging out with various theoretical perspectives), omnipresence (treated as a universal or global phenomenon), and omnipotence (identified as the cause of a wide variety of social, politic...

Bone marrow-derived mesenchymal stromal cells (MSCs), beneficial for regenerative medicine applications due to their wide differentiation capabilities, also hold promise as cellular vehicles for the delivery of therapeutic plasma-soluble gene products due to their ease of handling, expansion, and genetic engineering. We hypothesized that MSCs, gene enhanced to express interleukin-12 (IL-12) and...

This study investigated the in vitro and in vivo radiation response of tumor cells transfected with human manganese Superoxide dismutase (MnSOD) cDNA. A major objective was to test the potential tumor suppressive effect of MnSOD in vivo. Tumor cells studied were an in vitro line derived from a murine spontaneous fibrosarcoma, FSa-II, which expressed an undetectable MnSOD activity. These cells w...

BACKGROUND Gene-poor, degenerate Y chromosomes have evolved repeatedly from ordinary autosomes, but little is known about the processes that silence most genes on an evolving Y. RESULTS Here, I quantify relative expression levels of 58 gene pairs on the recently formed neo-sex chromosomes of Drosophila miranda, in order to test competing models of gene inactivation on its newly evolving Y chr...

We now realize, from the case of 2008 TC3’s discovery and subsequent impact in Sudan, that it is much more likely that a Near Earth Object (NEO) large enough to cause damage on the ground will be found (by the current Spaceguard Survey telescopes) on its "death plunge," providing a couple weeks of warning, than that a dangerous NEO will be found years or decades before impact. We also understan...

Necrotizing external otitis (NEO) is an invasive infectious disease involving the cartilaginous and/or bony external auditory canal (EAC) that particularly affects immunocompromised patients.1 Patients usually present with unrelenting otalgia that is disproportionate to the clinical signs and purulent otorrhea. The diagnosis of NEO is based on a combination of clinical, laboratory, and imaging ...

This study evaluates the validity of derived measures of the psychopathic personality traits of Fearless Dominance and Impulsive Antisociality from the NEO Personality Inventory-Revised (NEO-PI-R; Costa & McCrae, 1992) using data from the Collaborative Longitudinal Personality Disorders Study (baseline N = 733). These 3 issues were examined: (a) the stability of the measures over a 10-year inte...