BACKGROUND The nosology of the psychosis high-risk state is controversial. Traditionally conceived as an 'at risk' state for the development of psychotic disorders, it is also conceptualised as a clinical syndrome associated with functional impairment. AIMS To investigate meta-analytically the functional status of patients at high clinical risk for psychosis and its association with longitudi...

will propose a prohibition on industry sponsored reviews when he speaks at the Barcelona meeting. One important group, until now silent in this debate, are the public agencies who currently provide a large part of the collaboration's core funding. In England, the Department of Health's funding is signed off by the director of research and development, John Pattison. " It seems perfectly legitim...

1. Thirty moderately severely hypertensive patients were studied in a double-blind comparison of minoxidil and hydrallazine in combination with frusemide and propranolol. 2. Blood pressure control in both groups of patients was satisfactory but long-term control appeared to be better in the minoxidil group. 3. Renal function was well preserved in both groups. Evidence of cardiac hypertrophy was...

BACKGROUND AND AIM Colorectal cancer (CRC) is the third leading cause of cancer mortality worldwide and laparoscopic colectomy has been established as equivalent to the open approach in terms of oncological results and patients' safety. Survival benefits have been reported in favor of laparoscopic colectomy (LC) in stage III CRC patients. Different immune responses after surgery, in terms of in...

Allografts eliminate the disadvantages associated with autografts and synthetic scaffolds but are associated with a disease-transmission risk. Therefore, allograft sterilisation is crucial. We aimed to determine whether polyvinylpyrrolidone-iodine (PVP-I) can be used for sterilisation and as a new wet-preservation method. PVP-I-sterilised and preserved allografts demonstrated improved mechanica...

canids are reservoir for some zoonoses helminthic disease. they are one of main public health problem. theaim of this study was to ascertain frequency of gastrointestinal helminthic infection of stray dogs in zabol city,southeaster of iran. in this descriptive study, 30 stray dogs were euthanized, intestine was removed by necropsy.then, the intestines was opened by scalpel and their contents pa...

AIM To compare Institut Georges Lopez (IGL-1) and Celsior preservation solutions for hepatic endothelium relaxation and liver cold ischemia reperfusion injury (IRI). METHODS Two experimental models were used. In the first one, acetylcholine-induced endothelium-dependent relaxation (EDR) was measured in isolated ring preparations of rat hepatic arteries preserved or not in IGL-1 or Celsior sol...