In this thesis, I present a computational neural model that reproduces the high-level behavioural results of well-known fear conditioning experiments: first-order conditioning, second-order conditioning, sensory preconditioning, context conditioning, blocking, firstorder extinction and renewal (AAB, ABC, ABA), and extinction and renewal after secondorder conditioning and sensory preconditioning...

The initial deposition of bacteria in most aquatic systems is affected by the presence of a conditioning film adsorbed at the liquid-solid interface. Due to the inherent complexity of such films, their impact on bacterial deposition remains poorly defined. The aim of this study was to gain a better understanding of the effect of a conditioning film on the deposition of motile and nonmotile Pseu...

We have addressed the source and nature of the persistent neural activity that bridges the stimulus-free gap between the conditioned stimulus (CS) and unconditioned stimulus (US) during trace eyelid conditioning. Previous work has demonstrated that this persistent activity is necessary for trace eyelid conditioning: CS-elicited activity in mossy fiber inputs to the cerebellum does not extend in...

The aim of the study was to compare the behavior of seeded cells on synthetic and natural aortic valve scaffolds during a low-flow conditioning period. Polyurethane (group A) and aortic homograft valves (group B) were consecutively seeded with human fibroblasts (FB), and endothelial cells (EC) using a rotating seeding device. Each seeding procedure was followed by an exposure to low pulsatile f...

An appropriate mesh selection strategy is one of the fundamental tools in designing robust codes for differential problems, especially if the codes are required to work for difficult multi scale problems. Most of the existing codes base the mesh selection on an estimate of the error (or the residual). Our strategy, based on the estimation of two parameters characterizing the conditioning of the...

We study the performance of firstand second-order optimization methods for `1-regularized sparse least-squares problems as the conditioning of the problem changes and the dimensions of the problem increase up to one trillion. A rigorously defined generator is presented which allows control of the dimensions, the conditioning and the sparsity of the problem. The generator has very low memory req...

The cerebellum provides a temporal computation for a number of tasks. We have found that the accuracy in timing motor responses is correlated across different motor effectors. Moreover, perceptual acuity in judging durations of auditory intervals is correlated with motoric measures of timing. These results suggest a common process underlying timing of different sorts, and that this process may ...

In this article we deal with two-locus nonparametric linkage (NPL) analysis, mainly in the context of conditional analysis. This means that one incorporates single-locus analysis information through conditioning when performing a two-locus analysis. Here we describe different strategies for using this approach. Cox et al. [Nat Genet 1999;21:213-215] implemented this as follows: (i) Calculate th...

objective(s) single injection of naloxone, a selective antagonist of morphine, prior to the drug conditioning testing was used to investigate on morphine dependence. materials and methods conditioning to morphine (2.5-10 mg/kg, s.c.) was established in adult male wistar rats (weighing 200-250 g) using an unbiased procedure. nitric oxide agents were microinjected into the central amygdala prior ...

sludge drying bed is preferred to mechanical methods due to the need for very simple technology. due to restriction of natural dewatering, we tried to eliminate some of these limitations by the tests and studies of assumptions. in this study, the effect of hydrostatic suction and sludge chemical conditioning has been studied in the natural sludge dewatering optimization. at first, hydrostatic s...