CTCF is a highly conserved zinc finger protein implicated in diverse regulatory functions, including transcriptional activation/repression, insulation, imprinting, and X chromosome inactivation. Here we re-evaluate data supporting these roles in the context of mechanistic insights provided by recent genome-wide studies and highlight evidence for CTCF-mediated intra- and interchromosomal contact...

Indeed, optio is Weaver who is credited with the origin of the term molecular biology in 1938. Development of luteinizing hormone releasing hormone neurones.

The paper forms a rejoinder to the paper by David Weaver (‘Organic, incremental and induced paths to sustainable mass tourism convergence’). It fully agrees with David Weaver that a sustainable development of tourism should focus on sustainable mass tourism development and not, as is currently the case, so much on niche products labelled ‘sustainable’. However, it critiques Weaver’s operational...

THE possibility of using electronic calculators for the mechanization of the translation process was first seriously considered early in 1945. It occurred to Dr. Warren Weaver, then a director of the Rockefeller Foundation, that it might be possible to make use of, or to design, such machines for the high-speed mass translation of scientific publications. On July 15, 1949, Dr. Weaver wrote a me...

During decades the study of networks has been divided between the efforts of social scientists and natural scientists, two groups of scholars who often do not see eye to eye. In this review I present an effort to mutually translate the work conducted by scholars from both of these academic fronts hoping to unify what has become a diverging body of literature. I argue that social and natural sci...

Recursive-hierarchical systems are multi-level systems that constitute their systemic closure through recursion. Their unique systemic nature has been ignored for years, causing confusion about their activity. In semiotics, for example, the logic of signification has fallen prey to the post-modernists’ “hall of mirrors,” which fails to grasp the logic of in-between that underlies recursive-hier...

This paper presents a sample pertaining to the creation and the use of words in the field of Natural Language Processing (NLP) in the years 1949-1966. These words have been statistically sorted and the results could be taken as a proof that electronic processing of linguistic data leads to the diffusion of clear and concise words for describing a complex concept which would need a circumlocutio...

The fine structure of the cerebellum of weaver mouse was examined and the paucity of granule cells and their axons, the parallel fibers, was confirmed. Unexpectedly, however, the dendritic spines of the Purkinje cells which, in normal animals, are the postsynaptic mates of the parallel fibers, were present. Furthermore, their essential morphology and their staining reactions were indistinguisha...