نتایج جستجو برای: weakly er open function

تعداد نتایج: 1645733  

Journal: :Journal of Fluorine Chemistry 2022

Electrochemical study of Er(III)/Er and Yb(III)/Yb systems was independently investigated in molten LiF-CaF2 on inert electrode at 840 °C using cyclic voltammetry square wave voltammetry. Experimental results showed that two different behaviours were observed: Er(III) reduced into metal a one-step diffusion controlled process Yb(III) first Yb(II) then Yb. The electrochemical containing both Mo ...

Journal: :Folia histochemica et cytobiologica 2007
Hammouche Sadjia Thérese Gernigon-Spychalowicz Jean Marie Exbrayat

The sites of action and the physiological role of estrogens and progesterone in the ovary are poorly understood in Reptiles. We have undertaken a systematic study of the immunoexpression of classical oestrogen receptor (ER or ERalpha) and progesterone receptor (PR) in the female lizard during the reproductive cycle. During vitellogenesis, ER was not expressed in vitellogenic follicles whereas P...

2014
Miguel Sanchez-Alvarez Fabian Finger Maria del Mar Arias-Garcia Vicky Bousgouni Patricia Pascual-Vargas Chris Bakal

The function and capacity of the endoplasmic reticulum (ER) is determined by multiple processes ranging from the local regulation of peptide translation, translocation, and folding, to global changes in lipid composition. ER homeostasis thus requires complex interactions amongst numerous cellular components. However, describing the networks that maintain ER function during changes in cell behav...

2013
Gabriel Scherer Jan Hoffmann

Type systems hide data that is captured by function closures in function types. In most cases this is a beneficial design that enables simplicity and compositionality. However, some applications require explicit information about the data that is captured in closures. This paper introduces open closure types, that is, function types that are decorated with type contexts. They are used to track ...

2014
Xingyun Su Xin Xu Guangliang Li Bingyi Lin Jiang Cao Lisong Teng

Estrogen receptor-alpha36 (ER-α36) is a 36-kDa variant of estrogen receptor-alpha (ER-α) firstly identified and cloned by Wang et al in 2005. It lacks both transactivation domains (activation function 1 and activation function 2) and has different biological characteristics compared to traditional ER-α (ER-α66). ER-α36 primarily locates on plasma membrane and cytoplasm and functions as a mediat...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکی 1390

سرطان پستان شایع ترین سرطان در زنان ایرانی است. تومورهای پستان بر اساس بیان گیرنده استروژن آلفا (er) به دو گروه er منفی و مثبت تقسیم می شوند.این طبقه بندی به انتخاب مسیر درمانی بیماران کمک می کند، بطوریکه بیماران مبتلا به تومورهای پستان نوع er مثبت با روش های مبتنی بر هورمون درمانی (مانند درمان با داروی تاموکسی فن) درمان می شوند. تومورهای er منفی به هورمون درمانی پاسخ نمی دهند. با توجه به ماهیت...

2007
Francesca Prinari

We study the weak* lower semicontinuity properties of functionals of the form F (u) = ess sup x∈Ω f(x,Du(x)) where Ω is a bounded open set of R and u ∈ W 1,∞(Ω). Without a continuity assumption on f(·, ξ) we show that the supremal functional F is weakly* lower semicontinuous if and only if it is a level convex functional (i.e. it has convex sub levels). In particular if F is weakly* lower semic...

Journal: :Neuron 2017
Jaime de Juan-Sanz Graham T. Holt Eric R. Schreiter Fernando de Juan Douglas S. Kim Timothy A. Ryan

Although the endoplasmic reticulum (ER) extends throughout axons and axonal ER dysfunction is implicated in numerous neurological diseases, its role at nerve terminals is poorly understood. We developed novel genetically encoded ER-targeted low-affinity Ca2+ indicators optimized for examining axonal ER Ca2+. Our experiments revealed that presynaptic function is tightly controlled by ER Ca2+ con...

2015
Takushi Namba

endoplasmic reticulum (ER) is a multifunctional organelle that is specialized for lipid synthesis, Ca2+ homeostasis, and protein synthesis. Protein synthesis is a multistep process involving folding and manipulation of proteins as well as the exportation of proteins to an appropriate location. Several stress responses, such as metabolic and anaerobic stress, induce ER dysfunction and protein un...

2010
JOSEPH F. KENT

If G is a locally compact topological group, let BC{G) denote the set of real-valued, bounded, uniformly continuous functions on G with the compact-open topology. Using the fact that the distal (weakly distal) functions are the elements of BC(G) whose orbit closures are compact distal (point-distal) minimal sets, we can characterize compact distal and point-distal minimal transformation groups....

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