This research presents the results of a series of stability studies on freeze-dried formulations of human growth hormone (hGH). Chemical decomposition via methionine oxidation and asparagine deamidation as well as irreversible aggregation are characterized by HPLC. Water sorption isotherms, DSC thermograms, and pulsed proton NMR data are also obtained. No glass transition temperatures are obser...

We used a prospective, longitudinal cohort enrolled as part of a program evaluation to assess the relationship between drinking water microbiological quality and child diarrhea. We included 50 villages across rural Bangladesh. Within each village field-workers enrolled a systematic random sample of 10 households with a child under the age of 3 years. Community monitors visited households monthl...

Aim: Present study was undertaken for detection, isolation, characterization of the possible sources of faecal coliforms in street vended fresh fruit juices sold along the road sides of Bellary city, India and assessed its safety for human consumption. Materials and Methods: The samples of orange fruit juices were collected from the four different public hot spot areas of the city and subjected...

Drinking water quality monitoring programs aim to support provision of safe drinking water by informing water quality management. Little evidence or guidance exists on best monitoring practices for low resource settings. Lack of financial, human, and technological resources reduce a country's ability to monitor water supply. Monitoring activities were characterized in Cambodia, Colombia, India ...

Trace levels of PAH pollutants are difficult to detect in water samples due to their low solubility. During this study, SPE method was used to improve the detection of the PAH analytes. A Visipre SPE vacuum manifolds sample preparation method was used to clean-up the river water samples before analysis. Twelve samples were simultaneously extracted via the unit. This method is generally faster a...

background : the protozoan parasites cryptosporidium spp. and giardia are known to occur widely in both raw and drinking waters. they are two of the causative agents of waterborne out-breaks of gastroenteritis throughout the world. in the present study, a pcr assay and fa were developed for detection of cryptosporidium oocysts and giardia cyst in environmental samples. methods : we have detecte...

A procedure for the preparation of clarified Pawpaw Juice was developed. About 750ml Pawpaw pulp was measured into 2 measuring cylinders A & B of capacity 1 litre heated to 40C, cooled to 20C. 30mls pectinase was added into cylinder A, while 30mls distilled water was added into cylinder B. Enzyme treated sample (A) was allowed to digest for 5hours after which it was heated to 90C for 15 minutes...

Self-propelled autonomous micromachines have recently been tasked to carry out various roles in real environments. In this study, we expose the microjets to various types of water that are present in the real world, examples include tap water, rain water, lake water and sea water, and we sought to investigate their behaviors under real world conditions. We observed that the viability and mobili...

A polymerase arrest assay was designed to determine sites of adduction in the human p53 gene induced by incubation with fecal water. Significant formation of adducts was observed on p53 DNA after a 2-h incubation in fecal water from 10 of 17 samples studied. Large sample-to-sample variation was observed. The major sites of polymerase termination occurred at nucleotides 3' to guanine residues. A...

Water vapour transport properties of gypsum block are studied in dependence on relative humidity using inverse analysis based on genetic algorithm. The computational inverse analysis is performed for the relative humidity profiles measured along the longitudinal axis of a rod sample. Within the performed transient experiment, the studied sample is exposed to two environments with different rela...