STUDY OBJECTIVE To assess the performance of automatic sleep scoring software (ASEEGA) based on a single EEG channel comparatively with manual scoring (2 experts) of conventional full polysomnograms. DESIGN Polysomnograms from 15 healthy individuals were scored by 2 independent experts using conventional R&K rules. The results were compared to those of ASEEGA scoring on an epoch-by-epoch basi...

673 A NUMBER OF RECENT REVIEWS PROVIDE DETAILED DESCRIPTIONS OF THE ORGANIZATION OF THE NEUROLOGIC SUBSTRATES CONTROLLING SLEEP-WAKE systems.1-6 The reader is also referred to an extensive consideration of rapid eye movement (REM) sleep.7 Our recent minireview focused on developmental events related to the decrease in REM sleep, including its relationship to other developmental changes, the rol...

Histamine and its two receptors, histamine-gated chloride channel subunit 1 (HisCl1) and ora transientless (Ort), are known to control photoreception and temperature sensing in Drosophila. However, histamine signaling in the context of neural circuitry for sleep-wake behaviors has not yet been examined in detail. Here, we obtained mutant flies with compromised or enhanced histamine signaling an...

Flexible or 'fluid' cognitive processes are regarded as fundamental to problem solving and creative ability, requiring a specific neurophysiological milieu. REM-sleep dreaming is associated with creative processes and abstract reasoning with increased strength of weak associations in cognitive networks. REM sleep is also mediated by a distinctive neurophysiological profile, different to that of...

Wireless sensor networks are networks with low power nodes and limited processing. The main problem in these networks is energy. This resource is not replaceable or rechargeable. Therefore, optimal energy consumption for wsn protocols is a necessity. In a number of proposed protocols periodic sleep and wake is used for energy use reduction but these protocols result in increased end to end dela...

Much has been written about the unique Federalist aspects of cannabis legalization. However, there comparatively little published literature evolving state-local relationships regarding industry. In this paper, we examine relationship and ask: To what extent do local governments control production, distribution, or use recreational under state statutes? Did statutes empower restrict governments...

Three-dimensional flows over impulsively translated low-aspect-ratio flat plates are investigated for Reynolds numbers of 300 and 500, with a focus on the unsteady vortex dynamics at post-stall angles of attack. Numerical simulations, validated by an oil tow-tank experiment, are performed to study the influence of aspect ratio, angle of attack and planform geometry on the wake vortices and the ...

The cyclic AMP-response element binding protein (CREB) is an activity-dependent transcription factor important for synaptic plasticity and memory storage. Levels of phosphorylated CREB within the cortex are higher in waking than in sleep, suggesting that CREB plays a role in sleep/wake regulation in mammals. We tested the hypothesis that CREB is critical for sleep/wake regulation by examining b...

This mini-review article presents the remarkable progress that has been made in the past decade in our understanding of the neural circuitry underlying the regulation of sleep-wake states and circadian control of behaviors. Following a brief introduction to sleep architecture and physiology, the authors describe the neural circuitry and neurotransmitters that regulate sleep and cortical arousal...