نتایج جستجو برای: wake rhythm
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Disturbed sleep-wake cycle and circadian rhythmicity are associated with cancer, but the underlying mechanisms are unknown. Employing a tissue-isolated human breast xenograft tumor nude rat model, we observed that glycogen synthase kinase 3β (GSK3β), an enzyme critical in metabolism and cell proliferation/survival, exhibits a circadian rhythm of phosphorylation in human breast tumors. Exposure ...
Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome.
Recent progress in biological clock research has facilitated genetic analysis of circadian rhythm sleep disorders, such as delayed sleep phase syndrome (DSPS) and non-24-h sleep-wake syndrome (N-24). We analyzed the human period3 (hPer3) gene, one of the human homologs of the Drosophila clock-gene period (Per), as a possible candidate for rhythm disorder susceptibility. All of the coding exons ...
The circadian clock is a molecular network of genes and proteins that control biological timing. In the suprachiasmatic nucleus of the brain, this unique signaling pathway operates to control the 24-hour sleep-wake cycle. In the periphery, the circadian clock acts to regulate local functions that follow circadian rhythms. Indeed, the cardiovascular system of mammals follows a circadian rhythm, ...
Abstract Introduction Skin temperature manipulation with little or no change in core body affects sleep-wake states. However, the significance of 24-hour variation skin to sleep quality is unclear. We aimed evaluate whether circadian rhythm distal (DST) free-living conditions and provide additional evidence about relationship between thermal input Methods In this cross-sectional study 2,177 com...
background: exact determination between children's sleep habits and their growth could help us to prevent this risk factor of children's growth disorders. thus this research was performed to investigate the correlation between sleep habits and growth of preschool children in ahvaz- iran. materials and methods: in this cross-sectional study, the data was obtained by using available sam...
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