Objectives: To review 26 consecutive patients with sustained monomorphic ventricular tachycardia (VT) of left ventricular origin, who underwent direct VT surgery. Methods: Economic factors precluded the use of an implantable cardioverter defibrillator (ICD) in the majority of these patients, and the indication for surgery in 81% of patients was for failed medical drug therapy and 27% of patient...

BACKGROUND Volumetric capnography dead-space measurements (physiologic dead-space-to-tidal-volume ratio [VD/VT] and alveolar VD/VT) are considered more accurate than the more readily available time-based capnography dead-space measurement (end-tidal alveolar dead-space fraction [AVDSF]). We sought to investigate the correlation between volumetric capnography and time-based capnography dead-spac...

STUDY OBJECTIVES To determine whether the widely accepted concept of using lower tidal volume (Vt) values in patients with ARDS or obstructive lung disease has affected the pattern of ventilator settings in mechanically ventilated patients who do not have one of these conditions. DESIGN AND PATIENTS We performed a retrospective chart review of all patients who had experienced out-of-hospital ...

BACKGROUND To study the relationship of susceptibility to lung cancer with the gene polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1, GSTP1 and smoking status in Han and Mongolian populations of Inner Mongolia, an autonomous region of China. MATERIALS AND METHODS PCR-RFLP, allele-specific and multiplex PCR were employed to identify the genotypes of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 in a case-...

Background: The impact of vanishing twin (VT) syndrome on obstetric outcome is currently unknown. The aim of this study was to compare obstetric and neonatal outcomes of VT with singleton and twin deliveries after assisted reproduction and to evaluate the impact of VT on pregnancy outcome. Methods: We analyzed 130 births at our hospital between January 2000 and February 2012 that resulted from ...

BACKGROUND Prior studies evaluating the efficacy of catheter ablation of ventricular tachycardia (VT) among patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) have reported varied outcomes. More recently, studies have suggested that an epicardial ablation is necessary for improved outcomes after catheter ablation of VT. The overall objective of the present study wa...

We have previously demonstrated the feasibility of virtual-heart simulations in determining noninvasively optimal infarct-related ventricular tachycardia (VT) ablation targets and guiding clinical ablation. are now proceeding with AVERT-VT, an FDA-approved study for ten prospective patients. To develop end-to-end personalized computational modeling prediction pipeline enabling AVERT-VT to asses...

BACKGROUND Catheter ablation of ventricular tachycardia (VT) in arrhythmogenic right ventricular cardiomyopathy improves short-term VT-free survival. We sought to determine the long-term outcomes of VT control and need for antiarrhythmic drug therapy after endocardial (ENDO) and adjuvant epicardial (EPI) substrate modification in patients with arrhythmogenic right ventricular cardiomyopathy. ...

BACKGROUND Anesthesia sometimes suppresses ventricular tachyarrhythmias (VT) resistant to conventional pharmacological treatment. METHODS AND RESULTS To know (1) whether deep anesthesia inhibits abnormal repolarization-related VT and (2) if α2-adrenoreceptor (AR) agonistic action is associated with the antiarrhythmic effect of anesthetics, the incidence of VT in a rabbit model of acquired lon...