BACKGROUND Opioids have been shown to affect learning and memory processes. Different protocols of morphine withdrawal can substantially vary in their success to prevent opioid induced impairments of cognitive performance. In the present study, we report the effects of single and repetitive ultra-rapid detoxification (URD) on spatial learning and memory in morphine addicted rats. METHODS Morp...

      Diabetes mellitus is associated with disturbances of learning and memory and cognitive functioning. Aegle marmelos Corr. from Rutaceae family, is widely used in Iranian folk medicine for the treatment of diabetes mellitus. It decreases blood glucose level by improving glucose tolerance and also has lipid-lowering and antioxidant properties. Considering the beneficial antidiabetic...

Stening, E. 2016. The Influence of APOE ε4 on the Hippocampus and HippocampusDependent Memory. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Social Sciences 130. 85 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9685-2. APOE ε4 is the major genetic risk factor for Alzheimer’s disease, a dementia characterized by memory impairment and hippocampal atro...

Event-related potential (ERP) studies using the task-switching paradigm show that multiple ERP components are modulated by activation of proactive control processes involved in preparing to repeat or switch task and reactive control processes involved in implementation of the current or new task. Our understanding of the functional significance of these ERP components has been hampered by varia...

Diabetic cardiomyopathy is accompanied by metabolic and ultrastructural alterations, but the impact of the structural changes on metabolism itself is yet to be determined. Morphometric analysis of mitochondrial shape and spatial organization within transverse sections of cardiomyocytes from control and streptozotocin-induced type I diabetic Sprague-Dawley rats revealed that mitochondria are 20%...

A model of normal attentional function, based on the concept of competitive parallel processing, is used to compare attentional deficits following parietal and frontal lobe lesions. Measurements are obtained for visual processing speed, capacity of visual short-term memory (VSTM), spatial bias (bias to left or right hemifield) and top-down control (selective attention based on task relevance). ...

This paper presents an optimal kinematic design of a 3PRC (prismatic-revolute-cylindrical) spatial translational parallel manipulator with inclined actuator arrangement by formulating a multi-objective optimization problem. Three performance criteria’s namely Global Conditioning Index (GCI), Global stiffness Index (GSI) and Workspace volume are considered as the objective functions. A multi-obj...

Melt flow in continuous casting tundishes is normal[y characterized by a combined model. The model is used to analyze the residence time disttibution of fluid in a tundish, In this model, the fluid volume in tundish is considered to be consisting of the plug flow, well-mixed flow, and dead volumes. Although this model was proposed over 20 years ago, most researchers have either used it incorrec...

he main purpose of this research is to answer the question that "How neighborhood of Iran's trading partners will have an effect on Iran intra-industry trade? For this purpose, the impact of spatial neighborhood effects of 23 major trade partners on Iran’s intra-industry trade for the period of 1995-2014, has been investigated through Spatial Panel Econometric and Maximum Likelihood Estimator (...