BACKGROUND Despite their notorious diversity, biological cells are mechanically well characterized by only a few robust and universal laws. Intriguingly, the law characterizing the nonlinear response to stretch appears self-contradictory. Various cell types have been reported to both stiffen and soften, or "fluidize" upon stretch. Within the classical paradigm of cells as viscoelastic bodies, t...

Introduction: The skin is a biological component and main organ of the external environment has viscoelastic action with property being remodeled under pressure that operates against tissue. Muscle flaccidity due to an increase in muscle tone, having less resistance. handled treatment sagging cut, this resource produces improvement by reconditioning elasticity capacity tension tissues generatin...

BACKGROUND Previous studies suggest that mechanical feedback could coordinate morphogenetic events in embryos. Furthermore, embryonic tissues have complex structure and composition and undergo large deformations during morphogenesis. Hence we expect highly non-linear and loading-rate dependent tissue mechanical properties in embryos. METHODOLOGY/PRINCIPAL FINDINGS We used micro-aspiration to ...

Quantification of mechanical properties of human prostate tissue is important for developing sonoelastography for prostate cancer detection. In this study, we characterized the frequency-dependent complex Young's modulus of normal and cancerous prostate tissues in vitro by using stress relaxation testing and viscoelastic tissue modeling methods. After radical prostatectomy, small cylindrical ti...

Quantitative measurement of mechanical properties of cervix is an effective tool to diagnose cervical insufficiency, specifically in the last trimester of pregnancy when preterm birth is mostly probable to occur. The objective of this study was to characterize the viscoelastic behavior of rat cervix at different displacement levels and rates early in the last trimester of pregnancy. Distinct di...

Digital volume correlation (DVC) in combination with high-resolution micro-computed tomography (microCT) imaging and situ mechanical testing is gaining popularity for quantifying 3D full-field strains bone biomaterials. However, traditional time-lapsed (i.e., interrupted) cannot fully capture the dynamic strain mechanisms viscoelastic biological materials. The aim of this study was to investiga...