Opioids are some of the most effective pain-relieving drugs used in the clinical management of pain (Gilman et al. 1990). In addition to their analgesic effect, opioid peptides and alkaloids also affect a number of physiological functions including hormone secretion, neurotransmitter release, feeding, gastrointestinal motility, and respiratory activity (Pasternak 1988). Extensive physiological,...

Crucial to an understanding of the mechanism of cell replication is a knowledge of the manner in which intracellular and surface membranes develop between successive divisions . The application of zonal centrifugation to separate cells according to their size and hence their relative age (Warmsley and Pasternak, 1970) has enabled us to study the timing of these events by measuring changes in fo...

The use of intelligent nanocomposites in sensing and actuation applications has become quite common over the past decade. In this article, electro-thermo-mechanical nonlinear dynamic buckling of an orthotropic piezoelectric nanocomposite (PNC) cylindrical shell conveying viscous fluid is investigated. The composite cylindrical shell is made from Polyvinylidene Fluoride (PVDF) and reinforced by ...

Abstract Variational principles and variationally consistent boundary conditions are derived for a system of double Rayleigh beams undergoing vibrations subject to axial loads. The elastic layer connecting the modelled as three-parameter nonlinear Winkler–Pasternak with Winkler having linear components Pasternak only component. forced freely vibrating beam using semi-inverse approach. Hamilton’...

AMA Moszczyńska E, Baszyńska-Wilk M, Bogusz-Wójcik A, Pasternak-Pietrzak K, Mazur Wysocka-Mincewicz M. Metabolic status in children with Cushing’s disease and its relationship remission. Pediatric Endocrinology Diabetes Metabolism. 2023. doi:10.5114/pedm.2023.130026. APA Moszczyńska, E., Baszyńska-Wilk, M., Bogusz-Wójcik, A., Pasternak-Pietrzak, K., Mazur, & Wysocka-Mincewicz, (2023). https://d...

In this study, using the non-local elasticity theory, the buckling and vibration analysis of triple- walled ZnO piezoelectric Timoshenko beam on elastic Pasternak foundation is analytically investigated under magneto-electro-thermo-mechanical loadings. Using the Timoshenko beam free body diagram, the equilibrium equation of Timoshenko nano-beam model is obtained and solved by Navier’s method fo...

PURPOSE This in vitro study sought to compare the antifungal activity of melaleuca alternifolia oil and fluconazole mixed with a tissue conditioner. MATERIALS AND METHODS By testing several concentrations of fluconazole and melaleuca oil in Visco-gel, the minimum most effective concentration of each antifungal agent against Candida albicans was determined. Mean inhibition diameter (MID) was u...

In this article, a semi-analytical solution is provided to investigate the free vibration characteristics of rotating truncated conical shells surrounded by Winkler–Pasternak type foundation. It assumed that material shell composed epoxy as matrix and graphene nanoplatelets (GPLs) reinforcement dispersed in both thickness length directions shell. The modeled based on first-order shear deformati...