visceral leishmaniasis (vl) is a zoonotic disease caused by leishmania species. dogs are considered to be the main reservoir of vl. a number of methods and antigen-based assays are used for the diagnosis of leishmaniasis. however, currently available methods are mainly based on direct examination of tissues for the presence of parasites, which is highly invasive. a variety of serological tests ...

background: previous studies revealed that selectins play key roles in homing of immune cells to inflamed tissues and lymphatic organs. l-selectins are expressed on immune cells and interact with p and e selectins to homing to the tissues, hence, the polymorphisms within the gene of l-selectins may are associated with alteration in its expression. thus, the current cross-sectional analytical st...

background: visceral leishmaniasis (vl) as one of the most important human parasitic disease is endemic in some parts of iran. several cases of vl have been reported recently in the ilam province. the current study aimed to assess the pre-sent status of human vl in the region. methods: a random cluster sampling method was used to collect 456 serums samples from the children up to 12 years of ag...

The association between large tumor size and metastatic risk in a majority of clinical cancers has led to questions as to whether these observations are causally related or whether one is simply a marker for the other. This is partly due to an uncertainty about how metastasis-promoting gene expression changes can arise in primary tumors. We investigated this question through the analysis of a p...

Soft-tissue sarcomas spread predominantly to the lung and it is unclear how often FDG-PET scans will detect metastases not already obvious by chest CT scan or clinical examination. Adult limb and body wall soft-tissue sarcoma cases were identified retrospectively. Ewing's sarcoma, rhabdomyosarcoma, GIST, desmoid tumors, visceral tumors, bone tumors, and retroperitoneal sarcomas were excluded as...

BACKGROUND Visceral pleural invasion (VPI) is an adverse prognostic factor in non-small cell lung cancer (NSCLC); however, its effect in relation to tumor size remains under debate. To better understand the prognostic impact and potential consequences for staging, we examined correlations between VPI and clinicopathologic characteristics in patients with NSCLC, particularly those with lymph nod...

Localized hyperthermia therapy by high-energy radio-frequency waves was evaluated in malignant and adjacent normal tissue of 30 patients with 10 types of cancer. Hyperthermia was delivered to superficial and deep visceral cancers in awake patients who had refractory disease. Histological and clinical responses were recorded serially. Toxicity tests in dogs, sheep, and pigs showed that progressi...

Plexiform neurofibromas are benign tumors originating from subcutaneous or visceral peripheral nerves, which are usually associated with neurofibromatosis type 1. They are almost always congenital lesions and often cause the surrounding soft tissue and bone to grow aberrantly. We treated a 12-year-old boy who presented with asymmetric pectus excavaum and an anterior chest wall plexiform neurofi...

background: obesity and overweight, as the most common metabolic disorders, are great health problem during recent decades. obesity takes a role as independent or concordant risk factor for many diseases. so, it has a considerable share in burden of morbidities and mortalities. urbanization and its consequences in increasing of incomes and per capita energy uptake, besides the notable reduction...

toxocariasis or visceral larva migrans (vlm) is a parasitic infection resulting from the invasion of human visceral organs by nematode larvae of genus toxocara (dog ascaris). using gathered information of clinical manifestations, past history, biochemical and haematological tests, indirect fluorescence antibody test (ifa) and follow up of patients, totally 10 human cases (6 males and 4 females)...