Heme oxygenase-1 (HO-1) is an inducible enzyme that is expressed in response to physical and chemical stresses, such as ultraviolet radiation, hyperthermia, hypoxia, reactive oxygen species (ROS), as well as cytokines, among others. Its activity can be positively modulated by cobalt protoporphyrin (CoPP) and negatively by tin protoporphirin (SnPP). Once induced, HO-1 degrades iron-containing he...

in this paper we study the dynamics of hepatitis b virus (hbv) infection under administration of a vaccine and treatment, where the disease is transmitted directly from the parents to the offspring  and also through contact with infective individuals. stability of the disease-free steady state is investigated. the basic reproductive rate, $r_0$, is derived. the results show that the dynamics of...

introduction: foot-and-mouth disease (fmd) is a highly contagious and economically devastating viral disease of livestock that is categorized in list a of animal diseases by the world organisation for animal health (oie). vaccination is effective against fmd and the vaccine production centers largely use the industrial ultra-filtration and chromatography in order to remove the cellular proteins...

Guaiacol peroxidases (GP) are haem-containing enzymes participating in many physiological processes in plants. The expression pattern of these enzymes is organ-specific and developmentally regulated. Methods: The presence of GP activity in extract samples, prepared from Crocus sativus L. corms that were either dormant or rooting for 3, 6 and 10 days, was investigated. Results: Kinetic studies r...

We examined carbon monoxide (CO) delivery by carbon monoxide-releasing molecule 2 (CORM-2) or hemoglobin (Hb) on cellular oxygen sensing and mitochondrial respiration in bovine aortic endothelial cells (BAECs). CORM-2 reduced hypoxia-inducible factor-1α (HIF-1α) and endothelin-1 (ET-1) expression in normoxic and hypoxic cells, but while Hb alone significantly reduced HIF-1α stabilization in hyp...

Enterprises need a flexible and configurable IT architecture to meet complex business requirements agilely. For the purpose of bridging business modelling in build-time and application configuration in runtime seamlessly, a Conceptual Ontology-based Resource metaModel (CORM) is proposed. Firstly, a resource meta-model is built as a referred model to describe business elements and relationships....

in order to understand the effects of different organic and chemical fertilizer on stigma yield, corm characterstics and leaf dry matter yield (as a forage) of saffron (crocus sativus l.), an experiment was conducted in the research station of faculty of agriculture, ferdowsi university of mashhad, iran, in 2005-2009; as a randomized complete block design with 12 treatments and three replicatio...