Glavonoid-rich oil (GRO) derived from ethanol extraction of licorice (Glycyrrhiza glabra Linne) root has been reported to have beneficial effects on health. In this study, we aimed determine the effect long-term administration GRO metabolic disorders and elucidate molecular mechanism. Female obese, type 2 diabetic KK-Ay mice were fed diets supplemented with 0.3% or 0.8% (w/w) for 4–12 weeks. Mi...

The mammalian AML/CBFalpha runt domain (RD) transcription factors regulate hematopoiesis and osteoblast differentiation. Like their Drosophila counterparts, most mammalian RD proteins terminate in a common pentapeptide, VWRPY, which serves to recruit the corepressor Groucho (Gro). Using a yeast two-hybrid assay, in vitro association and pull-down experiments, we demonstrate that Gro and its mam...

The World Wide Web has made world a global village and internet of things (IoT) is making this place smarter and efficient by allowing the variety of sensors and smart objects to collect and process the information for various use. These smart objects are making healthcare system smarter and giving advantages to underdeveloped countries where basic health units do not have complete medical infr...

Approximately 15 different alpha, or CXC, chemokines have thus far been isolated from 11 species of mammals. Among the best studied chemokines are the 12 human proteins that are encoded by 11 paralogous genes. In order to better understand the evolution and function of this group of genes, we isolated and characterized six novel GRO and GRO-related cDNA sequences from the cow (Bos taurus), the ...

one of the innovations of councils law is the assignment of an executive officer is responsible of implementing legislations of islamic council of the village. the performances of assistants we classified in three classes of social, economical and environmental- structural indices. the objective of the current research is to evaluate the indices effective on the performance levels of village as...

© 2015 The Authors. This is an Open Access article. Traditionally, senescence in plants is defined as internally programmed degeneration or age-related declines in survival and reproduction, leading to death or variation in mortality patterns ��oach 200��. �lants �ith indeterminate gro�th, such as clonal plants or bryophytes, may escape determinacy of death or aging by continuous gro�th �ith pr...

Globalisation aims at bringing the world closer like a global village. But it has not had much impact on small-scale farming communities in Africa due to several barriers. These include illiteracy which hinders access to printed and electronic information; poverty which does not allow farmers to have the purchasing power to acquire equipment, such as television sets, radio sets, computer, etc, ...