OBJECTIVE To determine the cost-effectiveness of in-utero percutaneous Vesico Amniotic Shunt (VAS) in the management of fetal lower urinary tract obstruction (LUTO). DESIGN Model based economic analysis using data from the randomised controlled arm of the PLUTO (percutaneous vesico-amniotic shunting for lower urinary tract obstruction) trial. SETTING Fetal medicine departments in United Kin...

Sir, Patients affected by chronic B-cell lymphatic leukaemia (CBLL) and, more rarely, other oncohaematological diseases may present with papules, plaques, nodules and vesico-bullous lesions on exposed areas (1–3). These lesions are usually considered an exaggerated reaction to insect bites, although the patients not always had a history (except for the seasonal presentation of cutaneous finding...

OBJECTIVE The incorporation of bowel segments for urinary tract reconstruction may induce intestinal mucosal changes with the development of metabolic, nutritional, gastrointestinal and carcinogenic complications. The early histological and histochemical changes of the intestinal mucosa in contact with the feces-urine mixture, are evaluated in the present study. MATERIALS AND METHODS Twelve r...

We examined the subcellular localizations of NAD(P)H oxidase, a reactive oxygen species (ROS)-producing enzyme, in fetal membrane chorion laeve trophoblasts from preterm or term pregnant women with or without chorioamnionitis (CAM). Ultrastructural enzyme histochemistry for NAD(P)H oxidase was used. In fetal membranes without CAM, approximately one quarter of the chorion laeve trophoblasts (25....