28 Purpose: This study was carried out to analyze volumes and localization of vertebral 29 hemangiomas in T12-L5 levels on MRI in patients with low back pain. 30 Methods: Thoraco-lumbar MR images were examined retrospectively in a total of 150 31 patients. Hemangiomas observed in vertebral bodies on sagittal vertebral sections were 32 assessed and data were evaluated to get ratios regarding sex...

Previous studies in animal populations have shown that stunted neural and thymolymphatic growth early in development may result in permanently impaired neural and immune function, decreased body growth, vertebral wedging, and decreased life-span. In the human adult, small vertebral neural canal (VNC) diameters may reflect early stunted neural and immune development and impaired function that le...

BACKGROUND The definition of a vertebral fracture is usually based on the presence of a deformation of the vertebral body and this can be misleading in the presence of a fracture without radiologic collapse with the definition of occult osteoporotic vertebral fractures (OOVFs). STIR sequence of MRI images showing hyperintensity signal was the most confirmative screening examination used to dete...

BACKGROUND Studies of the effect of childhood obesity on bone accrual during growth have yielded conflicting results, largely related to the failure to adequately characterize the confounding effects of growth, maturation, and body composition. OBJECTIVE The objective of this study was to determine the effect of childhood obesity on skeletal mass and dimensions relative to height, body compos...

Bone morphogenetic proteins (BMPs), as well as the BMP-binding molecules Chordin (Chd), Crossveinless-2 (CV2) and Twisted Gastrulation (Tsg), are essential for axial skeletal development in the mouse embryo. We previously reported a strong genetic interaction between CV2 and Tsg and proposed a role for this interaction in the shaping of the BMP morphogenetic field during vertebral development. ...

PURPOSE To evaluate changes in vertebral marrow signal intensity that occur over time in children undergoing craniospinal radiation therapy, specifically evaluating for the occurrence and timing of marrow regeneration. METHODS MR images of nine pediatric patients (ages 4 to 12 years) with posterior fossa medulloblastoma who received total spinal irradiation (24 to 40 Gy) and had at least thre...

INTRODUCTION We describe a patient who had cervical spine osteomyelitis caused by Blastomyces dermatitidis that resulted in cord compression and cervical spine instability. CASE PRESENTATION A 25-year-old Hispanic woman presented with fever, sweats, neck pain, and an enlarging neck mass with purulent discharge after sustaining a C6 vertebral body fracture. Magnetic resonance imaging confirmed...

The aim of this study is to assess the effects of different glucocorticoid administration protocols on biomechanical properties of the first lumbar vertebral body in rats. We divided 40 male rats into the following groups: control, dexamethasone (7 mg/week), dexamethasone (0.7 mg/week), methylprednisolone (7 mg/kg/week), methylprednisolone (5 mg/kg twice weekly), dexamethasone (7 mg/kg three ti...

BACKGROUND The objective of this study is to identify the independent risk factors of neurologic deficit after thoracolumbar burst fracture. Traumatic fractures of the thoracolumbar spine are the most common type of spinal column fractures. Many studies have attempted to determine whether neurologic deficit in such fractures is related to spinal canal stenosis or other parameters observed on ax...

STUDY DESIGN A validated nonlinear three-dimensional finite element (FE) model of a single lumbar motion segment (L3-L4) was used to evaluate the effects of total disc replacement (TDR). The model was implanted with a fixed-bearing TDR (ProDisc-L) at 2 surgically relevant positions and exercised about the 3 anatomic axes. Facet forces, range of motion (RoM), and vertebral body strains were eval...