OBJECTIVE We aimed to assess the influence of Melissa officinalis (lemon balm), a well-known herbal drug with numerous applications in traditional and modern medicine, on cardiac conduction and susceptibility to lethal ventricular arrhythmia. MATERIALS AND METHODS Forty-two male Wistar rats were divided into a control group (CTL), an M. officinalis group that received the aqueous extract of M...

The Uygur herb, Hyssopus officinalis L., has been demonstrated to affect the levels of a number of cytokines in asthmatic mice, including interleukin-4, -6 and -17 and interferon-γ. In the present study, the effect of Hyssopus officinalis L. on airway immune regulation and airway inflammation was investigated in a mouse model of chronic asthma. A total of 32 BALB/c mice were randomly divided in...

Oryza officinalis has proven to be a natural gene reservoir for the improvement of domesticated rice as it carries many desirable traits; however, the transfer of elite genes to cultivated rice by conventional hybridization has been a challenge for rice breeders. In this study, the conserved sequence of plant stress-related NAC transcription factors was selected as a probe to screen the O. offi...

Melissa officinalis L. is a medicinal plant with a large variety of pharmacological effects and traditional applications. This study aimed to evaluate the protective and antioxidant activities of the extract of M. officinalis aerial parts on human umbilical vein endothelial cells (HUVECs) under oxidative stress induced by H2O2. Cells were incubated with H2O2 (0.5 mM, 2 h) after pretreatment wit...

BACKGROUND Several studies are conducted on Premenstrual Syndrome (PMS). However, a few herbal surveys exist on the treatment of PMS in Iran. Due to the sedative effects of Melissa officinalis (M. officinalis), this question comes to mind that "can it be used in the treatment of PMS symptoms?" OBJECTIVES The current study aimed to assess the effect of M. officinalis capsule on the intensity o...

This work describes an efficient micropropagation protocol for Verbena litoralis and the study of the antinociceptive and antioxidant activities in extracts of this species. For the establishment in vitro, surface-sterilization procedures and PVPP showed high efficiency in fungal-bacterial contamination and phenol oxidation controls. Nodal segments cultivation in MS medium supplemented with 6-b...

Fumaria officinalis is one of the herbal medicines used in Iran extensively. There are many useful properties recognized for this plant, but there is no information about its side effects especially in long term and at high doses. The objective of the present study was to investigate the effects of F. officinalis hydroalcoholic extract on the Blood Urea Nitrogen (BUN) and serum creatinine conce...

Rosmarinus officinalis L. is commonly used as a spice and flavoring agent. Diterpenes are the main active compounds of R. officinalis. An Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry (UHPLC-ESI-MS/MS) method was developed for the determination of carnosol, rosmanol, and carnosic acid isolated from R. officinalis in rat plasma, and applied to a pharmacokinetic study afte...

Introduction:Salvia officinalis L.is a plant growing and cultivated in some parts of Iran. The leaves of Salvia officinalis L.(Lamiaceae) are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic and diuretic as well as for functional gastrointestinal disorders. The aim of this study is to overview its therapeutic effects than its nutritive an...

Our objective is to evaluate the antibacterial and antioxidant activity of ethanolic extracts of Plectranthus mollis (P.mollis) and Salvia officinalis (S. officinalis) leaves locally used for treatment of microbial infection in Nilgiris of India. Antibacterial activity was determined by using agar diffusion and broth dilution methods against seven microorganisms. The antioxidant potential was a...