Henri Roger, in 1879, was the first to accurately describe the clinical manifestations of ventricular septal defect, and the term “maladie de Roger” is often used in connection with these malformations. The lesion and the problems associated with it have attracted a great deal of attention in recent years, particularly with the advent of open heart surgery and a means for affecting a cure. Embr...

OBJECTIVE Preterm birth and cardiovascular malformations are the 2 most common causes of neonatal and infant death, but there are no published population-based reports on the relationship between them. We undertook this study to determine the prevalence and spectrum of cardiovascular malformations in a preterm population, the prevalence of prematurity among infants with cardiovascular malformat...

SJNCE the first open intracardiac repair of interventricular septal defects and tetralogy of Fallot,1 2 rapid progress has been made in operative technics and in extracorporeal perfusion technology. Operative risk has steadily declined, and recent communications indicate that in ventricular septal defects uncomplicated by pulmonary hypertention the mortality rate is approximately 2 per cent.3 5...

A case of attempted suicide is described which is believed to be the first reported example of survival after a self-inflicted penetrating knife wound of the heart. The 12 cm. blade entered the right ventricle and damaged one of the papillary muscles. The ventricular septum was also perforated. At cardiotomy the stab wound in the free wall of the right ventricle was surtured and the papillary m...