Real-time, two-dimensional echocardiographic studies were performed in 10 patients with acute myocardial infarction who had clinical features suggestive of right ventricular involvement. All patients showed right ventricular wall motion abnormalities. In the four-chamber view, seven patients showed akinesis of the entire right ventricular diaphragmatic wall and three showed akinesis of segments...

The analysis deals primarily with follow-up studies of patients who have had a valvulotomy for valvular pulmonic stenosis with an intact ventricular septum. In addition to observations on the subjective improvement, hemograms, and arterial oxygen saturation, the cardiac findings have been analyzed in detail. The changes in the size of the heart have been studied in relation to the growth of the...

BACKGROUND In patients with acute pulmonary embolism (PE), rapid and accurate risk assessment is paramount in selecting the appropriate treatment strategy. Right ventricular (RV) enlargement on chest CT has previously been shown to correlate with an unstable hospital course, but its role as a predictor of death is unknown. METHODS AND RESULTS We evaluated 431 consecutive patients (mean age, 5...

A consecutive series of 86 patients with an inverted T wave showing terminal positivity (overshoot) of a specific pattern in the resting electrocardiogram were studied. Patients with bundle branch block or electrocardiographic evidence of acute infarction and those taking digoxin or a similar drug were excluded. In 67 patients the heart was examined by echocardiography and in a further two by d...

BACKGROUND The mechanisms of ventricular enlargement and dysfunction during postinfarct remodeling remain largely unknown. Although global left ventricular architectural changes after myocardial infarction are well documented, differences in function between adjacent and remote noninfarcted myocardium during left ventricular remodeling have not been investigated. These functional differences ma...

BACKGROUND Left atrial (LA) enlargement is associated with adverse events in heart failure with preserved ejection fraction (HFpEF). However, the role of LA mechanics (ie, LA strain measures) in HFpEF has not been well studied. We hypothesized that in HFpEF, reduced (worse) LA strain is a key pathophysiologic abnormality and is a stronger correlate of adverse events than left ventricular or rig...

evidence of enlargement of the main pulmonary artery were assessed in all. We attempted to assess changes in the peripheral pulmonary arterial branches as recommended by Davies, Goodwin, Steiner, and Van Leuven (1953), but found in many cases this was too difficult to determine with sufficient certainty. The three criteria we have used (pulmonary hypertension, E.C.G. signs of right ventricular ...

Pressure-induced cardiac enlargement was created in neonatal (21 days of age) and adult (250-275 g) rats by abdominal aortic constriction. Sham-operated and aorta-constricted neonates were studied 2, 3, 4, and 5 weeks after surgery. Left ventricular weight was elevated by approximately 50% at all times studied. Radioautography demonstrated a marked elevation in H-thymidine-labeled nuclei in car...

The five patients presented were considered to have mitral stenosis because of a history of dyspnea on exertion or paroxysmal atrial fibrillation, the presence of a loud first heart sound with an "opening snap," a loud pulmonary component of the second heart sound, electrocardiographic evidence of right axis deviation and left atrial enlargement or radiological evidence of cardiomegaly, especia...

The relationship between renal volume and hypertension in autosomal dominant polycystic kidney disease (ADPKD) occurs in childhood. Hypertension is associated not only with increased kidney volume but also with significantly increased left ventricular mass index. Moreover, this increase in left ventricular mass index occurs in children who have ADPKD with borderline hypertension (75th to 95th p...