abstract : before initiating any endodontic therapy, probability of extra canals should be considered. the incidence of three canals in mandibular second premolar has been reported to be 0.46-0.5%. the present report describes nonsurgical endodontic treatment of three mandibular second premolars with three canals. in these cases, three orifices were located in mesiobuccal, distobuccal and lingu...

This publication deals with under-ventilated combustion regimes in case of pool fire a confined- and mechanically-ventilated enclosure. The objective is to improve the understanding ventilated compartment focusing on effect size ventilation rate. It based dodecane tests conducted reduced scale (1.875 m3) enclosure considering two varying parameters, diameter air flow rate prior ignition. Three ...

RATIONALE Density-based morphometric studies have demonstrated decreased capillary density in infants with bronchopulmonary dysplasia (BPD) and in BPD-like animal models, leading to the prevailing view that microvascular development is disrupted in BPD. OBJECTIVE To perform a comprehensive analysis of the early and late effects of ventilation on pulmonary microvascular growth in preterm infan...

Ventilating patients with acute respiratory failure according to standardized recommendations can lead to varying volume-pressure (V-P) relationships and overdistension. Young children may be more susceptible than adults to overdistension, and individual evaluation of the effects of ventilator settings is therefore required. Three studies have applied indices for the detection of overdistension...

Ventilation of preterm neonates causes pulmonary inflammation that can contribute to lung injury, propagate systemically and result in long-term disease. Modulation of this initial response may reduce lung injury and its sequelae. We aimed to determine the effect of human amnion epithelial cells (hAECs) on immune activation and lung injury in preterm neonatal lambs. Preterm lambs received intra...

BACKGROUND Current guidelines for management of patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease (COPD) recommend that clinical decisions, including escalation to assisted ventilation, be informed by an estimate of the patients' likely postdischarge quality of life. There is little evidence to inform predictions of outcome in terms of quality of life, psyc...

Purpose of review: This article reviews the thoracic complications from malpositioned blindly inserted nasogastric feeding tubes in mechanically ventilated patients in intensive care and the methods to check the position and promote safe placement of the feeding tubes. Recent findings: Malpositioned feeding tubes are not included in risk management databases. The reported incidence is 1-3% and ...

Among the devices employed for aerosol generation (metered-dose inhalers, nebulizers, and dry powder inhalers) only metered-dose inhalers and nebulizers are routinely employed for aerosol delivery to mechanically ventilated patients. The ventilator circuit and artificial airway were previously thought to be major barriers to effective aerosol delivery to mechanically ventilated patients. In the...

Mechanical ventilation (MV) and ventilator strategies can induce or aggravate lung injury and may contribute to the development of distant organ failure, including the gastrointestinal tract. A retrospective cohort study was performed among 61 preterm infants, with a gestational age of 25-36 weeks, admitted at a neonatal intensive care unit. Intestinal permeability was measured by the sugar abs...