Introduction . Fractures of the maxilla are characterized by such features as close location vital anatomical structures, visual organ, well aesthetic importance this area face and presence risk serious complications. The aim work was to estimate level angiogenic factors in oral fluid: vascular endothelial growth factor A (VEGF-A), D (VEGF-D), placental (PIGF), platelet-derived BB (PDGF-BB) (VE...

Background and AimLymphatic vessels (LVs) are crucial for maintaining abdominal fluid homeostasis immunity. In cirrhosis, mesenteric LVs (mLVs) dilated dysfunctional. Given the established role of VEGF-C in improving LVs, we hypothesized that treatment could ameliorate functions mLVs cirrhosis.MethodIn this study, developed a nanoformulation comprising LV-specific growth-factor, recombinant hum...

Local hyperadrenergic states after a random flap elevation mediated by humoral vasoconstrictors can lead to necrosis. This study aimed evaluate the effect of Botulinum Toxin A (BoNT-A) on reducing levels Norepinephrine (NE) as main vasoactive substance, well its additive with Vascular Endothelial Growth Factor (VEGF) in increasing viability flap. 28 Wistar Rats Caudally Based Modified McFarlane...

More VEGF, more life—and health span Advanced aging is celebrated but its ill effects, deterioration at the cell, tissue, and organ levels, are not. Grunewald et al . provide evidence for vascular theory of aging, which reports that age-related decrease function a driver organismal large (see Perspective by Augustin Kipnis). Vascular endothelial growth factor (VEGF) signaling insufficiency unde...

Background: Endometriosis is a disease which is defined by the growth of endometrium-like tissue outside of the uterine cavity. Literatures show that VEGF by interaction with their receptors, Flt-1 (Fms-like tyrosine kinase-1 or VEGFR-1) and Flk-1/KDR (fetal liver kinase/ kinase-insert domain receptor or VEGFR-2) is related to pathogenesis of endometriosis. The purpose of this study was to eval...

background: new blood vessels formation is a critical step in tumor progression. vascular density affects the clinical outcome and prognosis of malignant tumors. the aim of this study was to investigate the relation between the vascular endothelial growth factor (vegf) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (oscc).   method...

Abstract We evaluated changes in the complement system resulting from anti-vascular endothelial growth factor (VEGF) eyes with age-related choroidal neovascularization (CNV) including neovascular macular degeneration, pachychoroid neovasculopathy, and polypoidal neovasculopathy. measured concentrations of activation products (C3a, C4a), VEGF, monocyte chemotactic protein-1 aqueous humor during ...

Objective(s):Although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hUCM) transplantation post myocardial infarction (MI), but this stem cell resource has no potential to induce angiogenesis. In order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hUCM ...