Carcinoid heart disease was first described in 1954. It develops over 70% of carcinoid syndrome patients. Up to 20% patients with have pronounced at diagnosis. Cardiac involvement is usually well tolerated by Symptoms are associated secretion serotonin, tachykinin and other vasoactive substances the systemic circulation. Deposition fibrous tissue along tricuspid annulus leads ring constriction ...

To elucidate the hemodynamic, autonomic, vascular, hormonal, and local mechanisms involved in blood pressure (BP)–lowering effect of dynamic resistance training (DRT) prehypertensive hypertensive populations. The systematic search identified 16 studies involving 17 experimental groups that assessed DRT effects on BP and/or These mainly enrolled women middle-aged/older individuals. Vascular were...

The ganglioneuroma is a tumor of the sympathetic nervous system and may be associated with hypersecretion of vasoactive substances responsible for various symptoms and signs such as hypertension. The authors report a case of ganglioneuroma and a literature review, focusing on the most important aspects of diagnosis and therapy. The patient had recurrent symptomatic hypertensive crises, having p...

cing tumour, is physiologically foreseeable owing to the sudden deprivation of catecholamines, as well as deprivation of other tumour-secreted bronchodilator substances, such as adrenomedullin [4], vasoactive intestinal peptide or pituitary adenylate cyclase-activating peptide [5]. There are, however, few reports of respiratory problems in patients with pheochromocytoma and all, in contrast to ...

Myocardial infarction after wasp sting is a rare event and this complication has been described in only a few previous occasions. We report the case of a 77-year-old patient admitted to our hospital because of an anaphylactic shock after he was stung by a wasp on the fifth finger of the left hand. Within about half an hour he sustained an acute myocardial infarction. Possible pathogenetic mecha...

Peripheral autonomic and sensitive neurons projecting to the extrinsic smooth penile musculature of the pig were studied by means of retrograde tracing and single-labelling immunofluorescence methods. The fluorescent retrograde tracer Fast Blue was injected into the left retractor penis muscle, that was taken as an experimental model of the male genital smooth musculature, of 4 castrated pigs. ...

BACKGROUND Acute vigorous exercise, associated with increased release of plasma catecholamines, transiently increases the risk of primary cardiac arrest. We tested the effect of acute submaximal exercise on vasoactive substances and their combined result on platelet function. METHODS Healthy volunteers, hypertensive patients and patients with coronary artery disease (CAD) performed a modified...

Elucidation of the mechanism by which coronary flow is regulated has been attempted. Substances with coronary vasodilator or vasoconstrictor properties as well as those with inotropic or chronotropic effects on isolated frog hearts were sought in the coronary sinus blood of dogs. Blood draining normal, hypoxic or "overperfused" hearts was oxygenated in a dog lung or on a screen and perfused at ...

Cardiac ultrasound investigation of 68 prospectively studied patients with histologically proven midgut carcinoid tumors showed right heart disease in 66%. The abnormal findings included morphologic and functional aberrations of the tricuspid valve in 52% and 83%, respectively, right atrial and ventricular enlargement in 53% and 30%, and paradoxical systolic septal contractions in 19%. The pati...