Background: Type 2 diabetes Mellitus (T2DM) is a multifactorial, polygenic disease caused by impaired insulin secretion, insulin resistance and beta-cell dysfunction. Melatonin is a circadian rhythm regulator and any imbalance in its levels can be related to various metabolic disorders. Melatonin and the genetic variants of MTNR1B gene are reported to be associated with T2DM susceptibility. We ...

Background: Type 2 diabetes mellitus (T2DM) is the most common type of diabetes that was classically characterized by pancreatic β-cell dysfunction. Changes in circadian patterns is one of the reasons which can increase the occurrence of diabetes. Melatonin is one of the biological molecules which plays an important role in regulating the circadian clock and also an inhibitory effect on insulin...

بــا توجــه بــه مطــرح شــدن رویکــرد ایجــاد جریان هــای فکــری بــا محوریــت نقــش شــهروندان و پیــرو سیاســت بهره بــرداری مجــدد از ســاختمان های واجــد ارزش بــا حمایــت مقــام عالــی و...