BACKGROUND Pannus formation may disturb the leaflet movement of the prosthetic valve. CASE PRESENTATION A 61-year-old woman presented with exertional dyspnea. She had undergone mitral valve replacement with a bioprosthetic valve 31 years ago, which was replaced with a tilting disc valve 22 years ago. The present laboratory findings revealed hemolytic anemia. Echocardiography showed an increas...

BACKGROUND The closure sound of the ATS bileaflet mechanical valve is said to be quieter than that of the other mechanical valves. However, the reasons for this are still unknown. In this study, we investigated the reasons for the quietness of the ATS valve closure sound. PATIENTS AND METHODS The valve closure sound was evaluated in 70 patients and in another 70 patients in whom the SJM valve...

OBJECTIVES: The effect of performing aortic valve repair in combination with valve-sparing operation on the length of time for which patients are free from reoperation is unclear. The objective of this study was to determine if the performance of aortic valve repair during valve-sparing operation modified the freedom from reoperation time. METHODS: From January 2003 to July 2014, 78 patients ...

RATIONALE Formation of heart valves requires early endocardial to mesenchymal transformation (EMT) to generate valve mesenchyme and subsequent endocardial cell proliferation to elongate valve leaflets. Nfatc1 (nuclear factor of activated T cells, cytoplasmic 1) is highly expressed in valve endocardial cells and is required for normal valve formation, but its role in the fate of valve endocardia...

discussion the cholecystojejunocolic anastomosis with intussuscepted valve surgery could be considered as a forthcoming approach in the treatment of intrahepatic cholestasis. case presentation an 11-year-old girl with the diagnosis of pfic underwent cholecystoappendicostomy with myotomy operation. because of anastomosis stricture, she was reoperated with cholecystojejunocolic anastomosis and in...

Transcatheter valve implantation is a novel interventional technique, which was developed as an  alternative therapy for surgical aortic valve replacement in inoperable patients with severe aortic stenosis. Despite limited experience in using transcatheter valve implantation for mitral and aortic regurgitation, transapical transcatheter aortic valve implantation and valve-in-valve implantation ...

Use of transcatheter mitral valve replacement (TMVR) using aortic valves in clinical practice is limited to patients with failing bioprostheses and rings or disease associated severe annulus calcification. Whereas the use valve-in-valve TMVR appears be a reasonable alternative surgery at high surgical risk, much less evidence supports valve-in-ring valve-in-mitral calcification interventions. D...

Transcatheter aortic valve implantation is a novel treatment for severe aortic valve stenosis. Due to the recent use of this technology and the procedural variability, there is very little data that quantify the hemodynamic consequences of variations in valve placement. Changes in aortic wall stresses and fluid retention in the sinuses of Valsalva can have a significant effect on the clinical r...

ii) The control valve Manufacturer can only state the Inherent valve characteristics, which refer to the flowrate (F) – valve travel position (m or Z) relationship, when the pressure drop across the control valve (DPV) is constant. Note that the pressure drop across the control valve (DPV) can be almost constant only if the piping system pressure drop (DPS) is concentrated at the control valve ...

The paper describes tests carried out on disc valves in which the valve seat was withdrawn from the valve wh).le a pressure difference existed across the valve. Simultaneous measurements were made of the force on the valve, the pressure in the plenum chamber and the displacement of the seat from the valve. Force measurements are compared with values of force measured during continuous flow cond...