In view of our previous findings that a specific antidiuretic (V2) agonist, 4-valine-8-D-arginine vasopressin, acutely increased cardiac output and heart rate in dogs, we examined the hypothesis that interaction with V2-like receptors might contribute to the hemodynamic response seen after blockade of the vasoconstrictor (V1) effect of arginine-vasopressin in dehydrated dogs. After 48 hours of ...

An ab initio study of specific solvent effects on the electronic coupling element in electron transfer reactions. Specific solvent effects on the electronic coupling element for electron transfer are examined using two model donor–acceptor systems (Zn 2 ϩ and Li 2 ϩ) and several model ''solvent'' species (He, Ne, H 2 O, and NH 3). The effects are evaluated relative to the given donor–acceptor p...

Unfertilized and fertilized eggs of the sea urchin Lytechinus pictus were preloaded with [C]valine and exposed to individual solutions of each of the twenty 'coded' [C]amino acids in artificial sea water. After 1 h incubation the amount of radioactivity in the medium was determined. The radioactivity was effectively displaced by most of the other neutral [C]amino acids that are known to compete...

The solvent isotope effects on the reaction catalysed by rat-liver glucokinase have been studied. At low concentrations of glucose and high concentrations of MgATP2there is an inverse solvent isotope effect of 3.5. At high glucose concentrations there is a normal solvent isotope effect of 1.3. In 'HzO there is positive co-operativity with respect to glucose [Storer, A. C. and Cornish-Bowden, A....

A recently developed method to calculate singlet and triplet gauge-origin]independent magnetic properties of solvated molecules is applied to the study of those parameters that determine an observed nuclear magnetic resonance signal: the magnetizability, the nuclear shieldings, and the indirect spin]spin coupling constants. The solvent is represented by a dielectric medium and the electronic st...

This paper presents a survey of significant developments in research on the leaching of oil paint films by organic solvents, from the first systematic investigations carried out in the 1950s to more recent “clinical” studies involving the sampling and analysis of paintings during treatment. Key studies are discussed in the context of an improved knowledge of oil paint chemistry that has develop...