Mesoangiobasts are blood vessel-derived stem cells that differentiate into smooth, skeletal, and cardiac muscle cells. We have reported that postnatal aorta-derived mesoangioblasts (ADM) regenerate skeletal muscle and prevent onset of dilated cardiomyopathy in animal models of Duchenne muscular dystrophy. ADM also differentiate into myelinating glial cells, suggesting they are multipotent and c...

Uterine leiomyomas are the most common benign pelvic tumors in women [1, 2]. They are monoclonal tumors of the smooth muscle cells of the myometrium and consist of large amounts of extracellular matrix that contains collagen, fibronectin and proteoglycan [2, 3]. A thin pseudocapsule that is composed of areolar tissue and compressed muscle fibers usually surrounds the tumors [4]. Leiomyomas may ...

Pulmonary benign metastasizing leiomyoma (BML) is a rare disease occurring predominantly in women of reproductive age and usually develops several years after the resection of a uterine leiomyoma. A 52-year-old postmenopausal woman was admitted to our hospital because of a right-sided empyema. Contrast-enhanced computed tomography showed a multiloculated pleural effusion on the right side and m...

BACKGROUND Leiomyomas are benign smooth muscle cell tumours. They are the most common uterine neoplasms, although they may also occur elsewhere, such as in the gastrointestinal and urinary tracts. Leiomyomas are uncommon in von Recklinghausen's neurofibromatosis (NF1). However, the literature suggests that the association of NF1 and leiomyomas or leiomyosarcoma is not entirely coincidental. C...

The objective of these studies was to define the roles of calcium and sodium in uterine smooth muscle excitation. The double sucrose-gap technique was used for current-clamp and voltage-clamp experiments. It was shown that neither sodium nor calcium alone is capable of supporting excitation in estrogen-dominated uterine smooth muscle. Calcium dependence was explained in part by increased membra...

The potassium contracture in the longitudinal muscle of estrogen-treated rat uterus was kinetically investigated. The rates of tension development after Ca addition and relaxation after Ca removal were measured under the high-potassium depolarization. Both rates decreased with an increase in preparation thickness. The relaxation rate had only a slight dependence on temperature. On the contrary,...

These studies have developed and tested an experimental approach to the study of membrane ionic conductance mechanisms in strips of uterine smooth muscle. The experimental and theoretical basis for applying the double sucrose-gap technique is described along with the limitations of this system. Nonpropagating membrane action potentials were produced in response to depolarizing current pulses un...

Uterine fibroids are the most common benign tumours in reproductive system. They proliferations of smooth muscle cells myometrium containing a large quantity extracellular matrix and they surrounded by pseudo capsule compressed areolar tissue cells. can cause various symptoms such as menorrhage, pain infertility therefore be traumatic experience for several women. The treatment choice is myomec...

Uterine fibroids ranked as the major reason for hysterectomy. leiomyomata (also called and myomas) represent localized proliferation of smooth muscle cells surrounded by a pseudocapsule compressed fibers. Fibroids are dependent on estrogen progesterone to grow therefore relevant only during reproductive years, they expected shrink after menopause. In India prevalence uterine (fibromyoma/leiomyo...

Lendometriose se definit par lexistence de tissu endometrial en dehors la cavite uterine. Sa localisation parietale est rare, pouvant survenir sur toutes les cicatrices surtout apres une intervention chirurgicale gynecologique, obstetricale ou encore abdominale [1].Lendometriose paroi a ete decrite dans differentes localisation: muscles grands droits labdomen, lombilic [1], cesarienne [2]. repr...