Background. The purpose of this study was to investigate urinary uromodulin (uUmod) excretion, reactivity the autonomic nervous system and impaired renal blood circulation in patients with predialysis chronic kidney disease (CKD), effect antioxidant therapy on these parameters. Materials methods. Ninety-one CKD stage 1–5 took part ROLUNT (UROmoduLin UbiquinoNe GlutaThione) study, their average ...