The kidneys are probably the only vital organs that are commonly affected by the precipitation of uric acid in patients with gout. Microscopic crystals of uric acid can sometimes be demonstrated in the collecting tubules, along with macros^opic concretions or calculi in the medulla and pelvis (Lichtenstein, Scott, and Levin, 1956; Talbott and Terplan, 1960; Gonick, Rubini, Gleason, and Sommers,...

Potassium citrate is prescribed to decrease stone recurrence in patients with calcium nephrolithiasis. Citrate binds intestinal and urine calcium and increases urine pH. Citrate, metabolized to bicarbonate, should decrease calcium excretion by reducing bone resorption and increasing renal calcium reabsorption. However, citrate binding to intestinal calcium may increase absorption and renal excr...

PURPOSE The aim of this study was to evaluate the biochemical stone composition in general population of Qom province, central Iran, and its relationship with high tap water hardness. MATERIALS AND METHODS In a prospective study, from March 2008 to July 2011, biochemical analysis of urinary stones in patients living in Qom province for at least 5 years was performed. Stones were retrieved by ...

Urine volume is the greatest risk factor for nephrolithiasis. High fluid intake is the first general advice given to stone-forming patients for the prevention of their recurrence. The aim of the present study was to evaluate the influence of bicarbonate-rich mineral water (1715 mg bicarbonate/l) on urinary-stone risk factors in comparison with sodium potassium citrate, a well-established treatm...

conclusions abnormal transaminases and uric acid levels are seen in ahf patients. increased ast levels may be a predictor of the need for inotrope during hospital course in these patients. patients and methods a total of 100 patients (aged 16 - 90 years, 60% men) admitted with ahf were enrolled. lfts and uric acid levels were assessed on first day and before discharge, and patients were followe...

The treatment of renal stone disease is very dependent on the composition of the stone. Uric acid stones for example have a completely differerent eitiology and treatment pathway to calcium phosphate or oxalate stones. Until now, the diagnosis of renal stone disease was mainly done through urine analysis and formal stone analysis once the stone has been removed. There is now a novel method of a...

a sensitive and selective kinetic-spectrophotometric method was developed for the determination of trace amounts of uric acid. the method is based on the inhibitory effect of uric acid on the oxidation of janus green by bromate in the presence of sulfuric acid. the reaction was followed spectrophotometrically by measuring the absorbance at 518 nm using the fixed-time method. under optimum exper...

Incidence of urinary calculi and its composition have been showing a remarkable global variation with profound changes in living standards and dietary habits. Indian urinary stone composition is usually different from that of the western countries. Urinary calculi in northern India were composed of pure calcium oxalate monohydrate (COM) and pure calcium oxalate dihydrate (COD) and in Bihar were...

rough-and-ready order of pathologists to assert the origin of vesical calculus in " salts in the drinking-water." The theory commends itself by its beautiful simplicity: the patient takes in " stone " at one end and passes it (or fails to do so) at the other, and makes as little demand upon the thoughtful intelligence of those who accept it as it received in the process of its conception. In th...