UNLABELLED Although Upper GI endoscopy is commonly performed in adults, paediatric endoscopy is not available in many of our referral centres. The efficacy and safety of upper GI endoscopy in paediatric age group performed in adult suite of Kathmandu Medical College is reviewed. PATIENTS AND METHOD A retrospective study of endoscopies performed on children aged up to 15 years in an adult endo...

OBJECTIVES/HYPOTHESIS To describe and to assess reproducibility of a method to model the lumen of the pharyngeal airway using anatomic structures. STUDY DESIGN Single-center, institutional review board-approved retrospective case series. METHODS Multiple structural landmarks (hard palate, palatal aponeurosis, genu, velum, and lateral wall; pharyngeal and vallecular tongue base; and epiglott...

Complications related by upper endoscopy include bleeding, perforation and infections but they are rare on simply diagnostic endoscopy. Duodenal perforation is less common but mortality rates are high. Diagnosis is based on keeping high suspicion that makes early detection to offer optimal treatments and better outcomes. Surgical intervention is standard treatment but some cases could benefit f...

OBJECTIVES/HYPOTHESIS Our study evaluates the efficacy of extraluminal bioresorbable plates to treat refractory localized airway malacia in patients undergoing corrective surgery for complex multilevel laryngotracheal stenosis. STUDY DESIGN Retrospective case series. METHODS Secondary malacic airway segments were characterized (severity, site, type) by a dynamic transnasal flexible laryngot...

Background: Hepatitis C virus infection (HCV) is a main health problem in our country. It is thought that the transmission of hepatitis C virus (HCV) through the endoscopic procedures is a rare event. The aim of this study was to evaluate the risk of conventional disinfection in the transmission of HCV. Materials and methods: A prospective study, comprising 456 consecutive upper gastrointestin...

BACKGROUND There are no prospective studies that have examined for chronic cough in children without lung disease but with gastroesophageal reflux (GER). In otherwise healthy children undergoing flexible upper gastrointestinal endoscopy (esophago-gastroscopy), the aims of the study were to (1) define the frequency of cough in relation to symptoms of GER, (2) examine if children with cough and r...

BACKGROUND The involvement of secretoglobins (SCGBs) other than SCGB1A1 (Clara cell 10-kDa protein, CC10) in human airway diseases remains unexplored. Among those SCGBs, SCGB3A2 (uteroglobin-related protein 1, UGRP1) is particularly interesting, given its structure and function similarities with SCGB1A1 (CC10). The aim of this study was to investigate the expression regulation of SCGBs other th...

BACKGROUND Upper gastrointestinal endoscopy has been reported as a risk factor for the transmission of Helicobacter pylori. The aim of this study was to evaluate the possibility of transmission of H. pylori infection by upper gastrointestinal endoscopy in patients who had previously had such procedures in a low disinfection level environment. METHODS The study included 1082 patients. Patients...