objective: pseudomonas aeruginosa is the major cause of septicemia and wound infection in burned patients. immunotraphy is the best practical way for prevention and treatment of these infections. flagella as one of the most important bacterial virulence factors has important role in attachment, motility, chemotaxis and tlr-5-dependent immune response so that it propounded as a vaccine candidate...

poorly water-soluble drugs often suffer from limited or irreproducible clinical response due to their low solubility and dissolution rate. in this study, organic solvent-free solid dispersions (osf-sds) containing telmisartan (tel) were prepared using polyvinylpyrrolidone k30 (pvp k30) and polyethylene glycol 6000 (peg 6000) as hydrophilic polymers, sodium hydroxide (naoh) as an alkalizer, and ...

Background: Cardiovascular mortality and morbidity are high in chronic renal failure (CRF) patients. Increased dispersion of QT intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. This study was conducted to assess the effect of hemodialysis (HD) on corrected QT (QTc) intervals and their dispersions (QTd) in chronic hemodialyzed patients. Methods: Fifty-eight p...

In this paper, a new model based on the thevenin equivalent circuit for investigating the ultra-saturation phenomenon during the energization of a loaded power transformer is presented and its effect on the differential protection of the transformer is considered. The ultra-saturation phenomenon causes the mal-operation of the power transformer differential protection. So, the description a...

Aqueous dispersions of fullerene C60 were prepared from fulleride solutions in tetrahydrofuran, followed by air oxidation, transfer to water and solvent evaporation. Fulleride exposition produces charged THF that can be transferred produce aqueous dispersions, stable for months.

background: cardiovascular mortality and morbidity are high in chronic renal failure (crf) patients. increased dispersion of qt intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. this study was conducted to assess the effect of hemodialysis (hd) on corrected qt (qtc) intervals and their dispersions (qtd) in chronic hemodialyzed patients. methods: fifty-eight p...

Graphite is exfoliated in water to give dispersions of mono- and few-layer graphene stabilized by surfactant. These dispersions can be used to form thin, disordered films of randomly stacked, oxide-free, few-layer graphenes. These films are transparent with a direct current conductivity of up to 1.5 x 10(4) S m(-1). The conductivity is stable under flexing for at least 2000 cycles. The electric...

aim: to enhance the aqueous solubility of olanzapine by using the solid dispersion technique. solid dispersions of olanzapine were prepared by the dispersion method using using pgs and ssg as carriers. drug:carrier ratios such as 1:1, 1:2, 1:4, 1:6, 1:8 and 1:10 were tried for optimization. characterization was done by phase solubility, in vitro release, saturation solubility, permeation, wetta...