The transcription factor TWIST is an important factor in regulating epithelial-mesenchymal transition (EMT) and tumor metastasis. To explore the functions of TWIST in hypopharyngeal cancer, we investigated if overexpression of TWIST has an effect on FaDu cell morphology, and if alteration of TWIST has an effect on E-cadherin, N-cadherin, c-fos, MM...

Application integration via web portals is the most widely used and least expensive means for integrating enterprise applications and services. Component-based portals enable the composition of web pages from reusable portal components, where each component represents an independent application or service. This integration is often limited to components displayed on the same web page, to local ...

Page segmentation into text and non-text components is an essential preprocessing step before OCR operation. If this is not done properly, an OCR classification engine produces garbage text due to the presence of nontext components. This paper describes improvements to the text/image segmentation algorithm described by Bloomberg, which is also available in his open-source Leptonica library. The...

The wide-angle photo- and electroproduction of pions is investigated within the handbag mechanism in which γ (∗)N → πN0 amplitudes factorize into subprocess amplitudes,γ (∗) q πq0 , form factors representing 1/x-moments generalized parton distributions (GPDs). calculated to twist-3 accuracy taking account both 2- 3-body Fock components pion. cross-sections are compared experiment spin-effects d...

The effect of D-cycloserine on the establishment of twist states in Bacillus subtilis macrofibers was examined. Macrofibers produced in the presence of the drug differed in twist compared with those produced in its absence. The degree of twist alteration was dependent on the concentration of D-cycloserine in the growth medium. Macrofibers of different twist states representative of the entire t...

Basic helix-loop-helix (bHLH) transcription factors are known as key regulators for mesenchymal differentiation. The present study showed that overexpression of Twist-1, a bHLH transcription factor, suppresses bone morphogenetic protein (BMP)-induced osteoblast differentiation, and downregulation of endogenous Twist-1 enhances BMP signaling. Maximal inhibition of BMP signaling was observed when...