نتایج جستجو برای: tumorigenesis antiangiogenesis

تعداد نتایج: 25649  

Journal: :Blood 1999
A Vacca M Iurlaro D Ribatti M Minischetti B Nico R Ria A Pellegrino F Dammacco

The effects of vinblastine (VBL) on endothelial cell functions involved in angiogenesis, namely proliferation, chemotaxis, spreading on fibronectin (FN), secretion of matrix-metalloproteinase-2 (MMP-2) and MMP-9, and morphogenesis on Matrigel were tested in vitro, whereas its effects on angiogenesis were studied in vivo by using the chick embryo chorioallantoic membrane (CAM) model. In vitro, a...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2003
Hideo Morioka Lawrence Weissbach Tikva Vogel G Petur Nielsen Glynn T Faircloth Li Shao Francis J Hornicek

A combination therapy protocol using a marine chemotherapeutic and an antiangiogenic molecule was tested in a mouse tumor xenograft model for the ability to curtail the growth of a human chondrosarcoma (CHSA). Ecteinascidin-743 (ET-743), a marine-derived chemotherapeutic, was effective at slowing the growth of a primary CHSA. Plasminogen-related protein B, which antagonizes various endothelial ...

Journal: :Journal of Molecular Biology 2021

Genetics is at the basis of cancer initiation and evolution, but emerging evidence indicates that mutations are not sufficient to produce cancer, indicating a role for epigenetic contributions different stages tumorigenesis. While genetic tracks have been widely investigated, “drivers” remain vague definition. Gene-environment interactions can gene-regulatory programs dictate pathogenesis; this...

200420052006200720082009201020112012201320142015201620172018201920202021202220230100020003000

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید