Understanding how stochastic molecular fluctuations affect cell behavior requires the quantification of both behavior and protein numbers in the same cells. Here, we combine automated microscopy with in situ hydrogel polymerization to measure single-cell protein expression after tracking swimming behavior. We characterized the distribution of nongenetic phenotypic diversity in Escherichia colim...

Chemotaxis of single cells has been extensively studied and a great deal on intracellular signaling and cell movement is known. However, systematic methods to embed such information into continuum PDE models for cell population dynamics are still in their infancy. In this paper, we consider chemotaxis of run-and-tumble bacteria and derive continuum models that take into account of the detailed ...

Although the motility of the flagellated bacteria, Escherichia coli, has been widely studied, the effect of viscosity on swimming speed remains controversial. The swimming mode of wild-type E. coli is often idealized as a run-and-tumble sequence in which periods of swimming at a constant speed are randomly interrupted by a sudden change of direction at a very low speed. Using a tracking microsc...

In this paper, an experimental approach for acoustic characterization of a household heat pump tumble dryer is developed. The main noise sources including BLDC motor, centrifugal fan, drain pump, and ventilation duct were identified using camera survey based on beamforming, sound pressure level, directivity, laser Doppler vibrometer vibration velocity measurements. addition, reduction measures ...