Background: The incidence of tuberculosis (TB) has increased in recent years in both developed and developing countries. Skeletal tuberculosis occurs in approximately 1% of patients with tuberculosis. The present study aimed to evaluate the epidemiology of skeletal tuberculosis in Golestan province in northeastern Iran during 2005-2014.Methods: In the present retrospective study, the epidemiolo...

SUMMARY AND KEY RECOMMENDATIONS: The aim of these guidelines is to describe a practical but evidence-based approach to the diagnosis and treatment of central nervous system tuberculosis in children and adults. We have presented guidance on tuberculous meningitis (TBM), intra-cerebral tuberculoma without meningitis, and tuberculosis affecting the spinal cord. Our key recommendations are as follo...

tuberculosis (tb) still represents a major public health problem worldwide. the primary form of disease is most often localized to the lung. in a minority of patients, progressive pulmonary disease spreads to other organ systems through self inoculation via infected sputum, blood and lymphatic system, establishing the secondary form of tuberculosis . we present a patient that was referred to us...

Primary nasopharyneal tuberculosis is a rare disease which is commonly present with cervical lymphadenopathy. It is hard to differenciate the diagnosis of tuberculosis from nasopharyngeal carcinoma. Histologic and bacteriologic evaluation is required for diagnosis. A male patient at the age of nineteen applied to our clinic with the complaints of a mass in the neck, congestion in the nose, nigh...

Although generally rising in incidence, intestinal tuberculosis is still rare in western countries and due to unspecific manifestations mainly as ulcerations on endoscopy, diagnosis of intestinal tuberculosis is challenging. Within this report, we describe a case of severe intestinal tuberculosis radiologically and endoscopically masquerading as colorectal cancer with peritoneal carcinomatosis....

Background: Laryngeal tuberculosis (TB) is one of the most common complications of pulmonary tuberculosis, which increased for various reasons such as more prevalence of immune system suppression diseases, increasing the survival of the elderly, immigrants from high-risk areas and the appearance of atypical or resistant organisms over the past two decades, and its clinical pattern changed compa...

Objectives: To find out the average duration from onset of symptoms to the diagnosis and treatment of tuberculosis, reasons for diagnostic delay, its consequences, association of variables and formulation of recommendations. Design: Hospital based cross-sectional study, conducted on 115 randomly selected patients. Setting: Lyari Chest Clinic and Nazimabad Chest Clinic in Karachi. Results: In th...

The diagnosis of pulmonary tuberculosis and tuberculous pleurisy standard methods is difficult and slow. Now, high hopes to cells of T cells secreting interferon-gamma in response to antigens of Mycobacterium tuberculosis. Use of the immune response to TB diagnosis. A systematic review was performed of latest publications. Interferon-γ release assays (IGRA) on peripheral blood mononuclear cells...

miliary tuberculosis (tb) is due to hematogenous spread of mycobacterium tuberculosis. clinical manifestations are nonspecific and protean, depending on the predominant site of involvement.we evaluated the clinical manifestations of 15 patients with miliary tb. the diagnosis of miliary tuberculosis was based on the identification of miliary nodules on chest radiography and one of the three foll...