نتایج جستجو برای: trypanosoma evansi

تعداد نتایج: 13781  

Journal: :Memorias do Instituto Oswaldo Cruz 2004
Sergio Ibáñez-Bernal Gabriela Rodríguez-Domínguez Carlos Hugo Gómez-Hernández Jorge R Ricardez-Esquinca

The phlebotomine sand fly Lutzomyia evansi is recorded in Mexico for the first time. This species is a suspected vector of Leishmania infantum in other parts of its geographical range and was captured in a focus of American visceral leishmaniasis where the principal vector, Lu. longipalpis sensu lato, was also found. The relative public health importance of the two species in the study area (Ch...

Journal: :Memorias do Instituto Oswaldo Cruz 2005
Azael Saldaña Franklyn Samudio Aracelis Miranda Lissette M Herrera Sara P Saavedra Lorenzo Cáceres Vicente Bayard José E Calzada

A total of 206 serum samples from children (3-14 years old) living in the Amador County (La Chorrera District, Province of Panama) were screened by indirect immunofluorescence antibody test (IFAT) for the presence of antibodies against Trypanosoma cruzi. Positive sera were confirmed by recombinant enzyme-linked immunosorbent assay (ELISA) and Western blot analysis. The presence of blood trypano...

Journal: :The Journal of biological chemistry 2012
Huanchen Wang Stefan Kunz Gong Chen Thomas Seebeck Yiqian Wan Howard Robinson Sibylla Martinelli Hengming Ke

Trypanosoma cruzi phosphodiesterase C (TcrPDEC) is a potential new drug target for the treatment of Chagas disease but has not been well studied. This study reports the enzymatic properties of various kinetoplastid PDECs and the crystal structures of the unliganded TcrPDEC1 catalytic domain and its complex with an inhibitor. Mutations of PDEC during the course of evolution led to inactivation o...

Journal: :The Journal of biological chemistry 1998
R Pellé V L Schramm D W Parkin

N-Ribohydrolases, including the inosine-adenosine-guanosine-preferring (IAG) nucleoside hydrolase, have been proposed to be involved in the nucleoside salvage pathway of protozoan parasites and may constitute rational therapeutic targets for the treatment of these diseases. Reported is the complete sequence of the Trypanosoma brucei brucei iagnh gene, which encodes IAG-nucleoside hydrolase. The...

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