Cytochrome P450 monooxygenases (CYPs) are enzymes that play critical roles in the structural diversification of triterpenoids. To perform site-specific oxidations triterpene scaffold, CYPs require electrons transferred by NADPH-cytochrome reductase (CPR), which is classified into two main classes, class I and II, based on their difference. Lotus japonicus a triterpenoids-producing model legume ...

objective(s) current study was undertaken to investigate the analgesic and anti-inflammatory effects of the aqueous extract of teucrium chamaedrys in mice and rats. materials and methods for evaluating of analgesic and anti-inflammatory activity, we used the carrageenan- and dextran-induced paw oedema, acetic acid-induced writhing, tail flick and formalin pain tests. results the extract of t. c...

Hippophae rhamnoides L. (Elaeagnaceae) is a hardy, deciduous shrub with yellow or orange berries. H. rhamnoides contains a series of chemical compounds including flavonols, sterols, lipids, triterpenoids, etc. H. rhamnoides has been used as a traditional medicine for the treatment of cough, indigestion, and blood stasis in China. Macrophages play major roles in host defense, immunity, and infla...

Pseudolarolides U and V, two new triterpenoids, and four biogenetically related compounds, pseudolarolides E, F, K, and P were isolated from the roots of Codonopsis pilosula (Campanulaceae). Their structures were determined by spectroscopic data. The regulation of Sirtuin 1 (SIRT1) activity by all the isolated compounds was evaluated.

Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1-4 showed moderate inhibitory activity against the α-glucosidase (with IC₅₀ values ranging from 1,812 to 2,027 μM).

Purpose: To evaluate the contents of carotenoids, triterpenoids, and phenylpropanoids in different parts white bitter melon.Methods: We evaluated accumulation 2 10 11 melon, including fruits at four developmental stages using HPLC.Results: Charantin, lutein, rutin were main phenylpropanoids, respectively. The triterpenoids (momordicine charantin), carotenoids (antheraxanthin, violaxanthin, α-ca...

Two new highly oxygenated lanostane triterpenoids, ganoderic acid AP2 (1) and ganoderic acid AP3 (2), were isolated from the fruiting bodies of the fungus Ganoderma applanatum (Ganodermataceae), along with four known analogues, ganoderenic acids A, B, D and G (3-6). The structures of the new compounds were elucidated on the basis of extensive spectroscopic analysis.

2,3-Secofernane triterpenoids, alstonic acids A (1) and B (2), were isolated from the leaves of Alstonia scholaris together with an indole alkaloid, N(1)-methoxymethyl picrinine (3). Their structures were established from MS and NMR spectroscopic analyses and confirmed by single crystal X-ray diffraction analysis.

The date palm is widely known as a richer nutritional source and natural medical agent. Date fruit major of carbohydrates dietary fiber, it has contains proteins, minerals, vitamins, phenolic compounds, carotenoids, sterols, triterpenoids. beneficial potential this well in Arab countries even the world. many health benefits such Glucose-lowering potential, anti-cancer activity, antioxidant hypo...

Phytochemical studies of leaf of the herbs, Andrographis paniculata and Andrographis lineate (Acanthaceae) were carried out. Presence of phenolic compounds, flavonoids, alkaloids saponins and tannins and absence of steroids and triterpenoids have been reported there in this herbs for the first time.