نتایج جستجو برای: triptolide
تعداد نتایج: 676 فیلتر نتایج به سال:
Adventitious root cultures were developed from Tripterygium regelii, and growth conditions were optimized for the abundant production of diterpenoids, which can be collected directly from the medium. An analysis of publicly available transcriptome data sets collected with T. regelii roots and root cultures indicated the presence of a large gene family (with 20 members) for terpene synthases (TP...
Varios estudios proponen la nucleolina como un blanco alternativo para búsqueda y el diseño de nuevas terapias antitumorales o anticancerígenas. El objetivo este estudio fue evaluar compuestos con potenciales afinidades unión al ARN las nucleolinas mediante herramientas bioinformáticas. Se evaluaron diez los cuales tres moléculas (ácido betulínico, triptolide berberina) presentaron interacción ...
Triptolide (TP), a major extract of the herb Tripterygium wilfordii Hook F (TWHF), has been shown to exert potent pharmacological effects, especially an immunosuppressive effect in the treatment of rheumatoid arthritis (RA). However, its multiorgan toxicity prevents it from being widely used in clinical practice. Recently, several attempts are being performed to reduce TP toxicity. In this revi...
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