Dermatophytes are the most common agents of superficial mycoses that are caused by mold fungi. Trichophyton rubrum is the most common pathogen causing dermatophytosis. The immunology of dermatophytosis is currently poorly understood. Recently, our group investigated the interaction of T. rubrum conidia with peritoneal mouse macrophages. We found that macrophages phagocytose T. rubrum conidia re...

Trichophyton rubrum is an important cause of dermatomycoses. Molecular strain typing methods have recently been developed to address questions about epidemiology and source of relapse following treatment. This report describes the application of RAPD for molecular strain differentiation of this fungus utilizing the primers 1- (5'-d[GGTGCGGGAA]-3') and 6- (5'-d[CCCGTCAGCA]-3'). A total of five R...

Earth has been documented as a natural area for fungi which found as individual kingdom through innovation. In their growth, different culture media significantly affected mycelium and sporulation. The present investigation was conducted to examine the effect of different broth media on the mycelial growth and fungal sporulation of Trichophyton rubrum and Microsporum gypseum. In the present stu...

Interdigital foot infections are mostly caused initially by dermatophytes, yeasts and less frequently by bacteria. Erythrasma caused by Corynebacterium minutissimum can be confused with superficial mycoses. The aim of the study was to determine the prevalence of the etiologic agents of superficial mycoses and the frequency of Corynebacterium minutissimum in interdigital foot infections. All the...

This was a clinical-epidemiological and mycological study on 184 patients at the university hospital: 200 samples, 142 positive samples, 98 yeasts and 68 filamentous fungi. Candida parapsilosis (47%) and Trichophyton rubrum (38%) were prevalent. They were 100% sensitive to ketoconazole and 99% sensitive to amphotericin B. The highest prevalences were among women (80%), adults (62%) and toes (84%).

Sir, Dermatophyte infection of the penis and scrotum is rare. It is difficult to explain why the penile shaft is generally not involved in patients affected by tinea cruris. Glans penis involvement is considered even rarer, whereas dermatophytosis of the prepuce has not been reported in the literature. Here we report a patient who presented with scaly lesion on the prepuce, which on investigati...

Trichophyton rubrum is the most common dermatophyte of humans and normally colonizes the superficial layers of the epidermis (stratum corneum). Several proteinases with a possible role in the metabolism of host proteins have been purified from this fungus. The regulation of these enzymes and their role in fungal metabolism were studied at the biochemical level. General proteolytic (azocollytic)...

Nitrogen determinations, performed upon the mycelia of Trichophyton rubrum, indicated that both the total nitrogen to mycelial weight ratio and the protein nitrogen to mycelial weight ratio decreased as the age of the mycelia increased. An increase in nitrogen concentration in the medium produced an increase in the total nitrogen to mycelia weight ratio, but did not necessarily increase the pro...

Dermatophytosis is a trivial disease but has lot of psychological effect and a costly disease in terms of treatment. Though various species of dermatophytes produce clinically characteristic lesions, but a single species may produce variety of lesions depending upon site of infection. The present study was undertaken with following aim and objectives. Isolation and identification of different e...