Behavioral training (BT) is recommended as a supplementary preventive treatment for migraine. Online interventions have been successful in promoting health behavior change, the evidence for online BT in migraine is limited, however. This randomized controlled trial aimed to determine the post-treatment effectiveness of online BT (n = 195) compared to a waitlist control group (WLC; n = 173) on m...

SP600125 is an inhibitor of c-Jun NH2-terminal kinase (JNK), which plays a fundamental role in regulating animal development. Using SP600125 to deal with the mouse embryonic stem cells, it is revealed that the number of the ESC colonies decreased and the size became smaller. With treatment by SP600125, the proliferation of mouse ES cells is seriously inhibited for the cycle arrested in the G2/M...

Armstrong, Gray, and Ham (1) showed that growth of azo dye-induced liver tumors on the yolk sacs of chicken embryos was more likely if metastasizing tumors were used. By injecting such metastasizing tumors, we were able in 1951 to es tablish a tumor induced by 4-dimethylaminoazobenzene in transplantable form. Since then the tumor has become widely used in cancer research laboratories in this co...

Excessive sleepiness (ES) is a major but underestimated public health concern associated with significant impairments in alertness/wakefulness and significant morbidity. The term ES has been used in the sleep medicine literature for years, but due to its nonspecific symptoms (ie tiredness or fatigue), it frequently goes unrecognized or is misdiagnosed in primary care. In some cases ES arises du...

HIV elite suppressors (ES) or controllers are individuals achieving control of viremia by their natural immunological mechanisms without highly active antiretroviral therapy (HAART). Study of the mechanisms responsible for the immunological suppression of viremia in ES may lead to the detection of individuals with ES and the effective control of HIV infection. We hypothesize that plasma glycopr...

BACKGROUND Australian football (AF) is a highly intermittent sport, requiring athletes to accelerate hundreds of times with repeated bouts of high-intensity running (HIR). Players aim to be in peak physical condition for finals, with anecdotal evidence of increased speed and pressure of these games. PURPOSE However, no data exists on the running demands of finals games, and therefore the aim ...

BACKGROUND A recent trial showed that setting PEEP according to end-expiratory transpulmonary pressure (P(pl,ee)) in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) might improve patient outcome. P(pl,ee) was obtained by subtracting the absolute value of esophageal pressure (P(es)) from airway pressure an invariant value of 5 cm H(2)O. The goal of the present study was to compa...

there are many discrepancies around the effect of sex hormones on spatial learning and memory in rodents. the aim of the present study was to investigate the effects of chronic administration of estradiol (es) and testosterone (tes) on spatial memory in adult castrated male rats. cholinesterase activity of the hippocampus in treated animals was also measured to seek if hormonal treatment can ch...