Although controversial, the use of properly chosen antibiotics in Crohn's disease appears beneficial. Evidence supporting the use of targeted antibiotic therapy comes in two forms: statistical evidence derived from meta-analyses of multiple formal studies and the documented clinical and endoscopic responses in patients treated with antibiotic combinations outside of formal clinical studies. Thi...

Extraosseous Ewing sarcoma (EOES) is an infrequent type of soft tissue sarcoma, which is highly chemosensitive and radiosensitive. It resembles Ewing sarcoma (ES) of bone histopathologically. The purpose of this study was to demonstrate the characteristics and clinical outcomes of children with EOES treated in a single centre, the largest state hospital that accepts oncologic patients. Patients...

Introduction Gallbladder perforation (GBP) is a rare disease with potential mortality. Previous series have reported an incidence of approximately 2-11% and it still continues to be a significant problem for surgeons. Aim To present our clinical experience with gallbladder perforation. Material and methods The records of 2754 patients who received surgical treatment for cholelithiasis betwe...

OBJECTIVE Treatment of intracranial dural arteriovenous fistulas (dAVFs) remains a challenge. However, after introduction of Onyx, transarterial approach is the preferred treatment option in many centers. We report our experience of dAVFs embolization with special emphasis on transarterial approach. METHODS Seventeen embolization procedures were performed in 13 patients with dAVFs between Jan...

BACKGROUND AND AIMS Endoscopic Interventional Treatment is of little trauma and less complications in the treatment of gastric schwannoma and leads to faster recovery and fewer days of hospitalization. This study was aimed to investigate the safety and efficacy of endoscopic interventional therapy for gastric schwannoma, including endoscopic submucosal excavation, non-laparoscopic-assisted endo...

The non–receptor protein tyrosine, Src, is a 60-kDa protein that is the archetypal member of a nine-gene family, including Src, Yes, Fyn, Lyn, Lck, Hck, Fgr, Blk, and Yrk, that plays a critical role in regulation of proliferation, differentiation, migration, adhesion, invasion, angiogenesis, and immune function (for detailed reviews, see refs. 1–4). All Src family kinases are myristoylated at t...

BACKGROUND Percutaneous pulmonary valvuloplasty is well established treatment of choice in pulmonary valve stenosis. AIM The aim of our study was to present our experience with the interventional technique, its immediate and mid-term effectiveness as well as its complication rate. MATERIAL AND METHODS The study included 43 patients, where 33 (74%) of them were children between the age of 1 ...

Introduction Jejuno-ileal atresia is the most common cause of congenital intestinal occlusion in newborns and the duodenal atresia is the most common cause of high bowel obstruction in the neonatal period. Nowadays the minimally invasive approach has been widely diffused and these surgical options are possible: circumbilical incision, the video-assisted and totally laparoscopic treatment. We pr...

OBJECTIVE To compare the estimated cost of treatment of spinal disorders to those of this treatment in a specialized center. METHODS An evaluation of average treatment costs of 399 patients referred by a Health Insurance Company for evaluation and treatment at the Spine Treatment Reference Center of Hospital Israelita Albert Einstein. All patients presented with an indication for surgical tre...

OBJECTIVE Sociodemographic and psychopathological characteristics as well as treatment approaches to patients at an outpatient clinic for drug addicts are described. METHODS Descriptive study based on randomly sampled medical charts and registration forms of subjects presenting for treatment from 1986 to 1993. RESULTS The sample was made up predominantly of young white unmarried men, with l...