[Purpose] The purpose of this study was to investigate the effects of treadmill training with a horizontal impeding force applied to the center of upper body mass on the gait and balance of post-stroke patients. [Subjects and Methods] Twenty-four subjects with hemiplegia less than 3 months after stroke onset were randomly assigned to 2 groups: an applied horizontal impeding force on treadmill t...

Postpartum depression (PPD) is defined as the depressive symptoms that occur from the moment of delivery until 12 months after delivery. PPD symptoms are closely associated with reduced activity of the serotonergic system. Serotonin (5-hydroxytryptamine, 5-HT) plays an important role in the pathogenesis of depression. Tryptophan hydroxylase (TPH) catalyzes the rate-limiting step of 5-HT biosynt...

The genetic and molecular events associated with changes in muscle mass and function after SCI and after the implementation of candidate therapeutic approaches are still not completely known. The overall objective of this study was to identify key molecular pathways activated with muscle remodeling after SCI and locomotor training. We implemented treadmill training in a well-characterized rat m...

Diabetes mellitus is associated with the impairment of sexual function including desire and orgasmic dysfunction. Sexual dysfunction in the diabetes mellitus is due to a selective defect of the nitric oxide synthase (NOS) within paraventricular nucleus (PVN). c-Fos is an immediate early gene and c-Fos expression represents neuronal activity in response to various stimuli. In the present study, ...

Treadmills are often used by runners when weather conditions are adverse or a specific training effect is desired. Athletes might respond to fatigue differently when running on a treadmill compared with overground conditions, where pace is typically more variable. The purpose of this study was to measure changes in gait parameters over the course of a 10-km treadmill run. Fifteen male competiti...

Treadmills are commonly implemented in rehabilitation and laboratory settings to facilitate gait analysis and training. However, while this locomotor modality is often used with children, its effect on pediatric stride interval dynamics is unknown. This study investigated the stride interval persistence of 30 asymptomatic children after completion of three to six 10-min walking trials comprised...

PURPOSE The development of efficient and independent walking is an important therapeutic goal for many children with cerebral palsy (CP). Consequently, there has been growing interest in determining the effects of treadmill training programs for these children. METHOD A systematic review of the literature was conducted to evaluate the effectiveness of treadmill training for children with CP. ...

Lower body positive pressure (LBPP) treadmill running is used more frequently in clinical and athletic settings. Accurate caloric expenditure is required for proper exercise prescription, especially for obese patients performing LBPP exercise. It is unclear if running on LBPP changes running economy (RE) in proportion to the changes in body weight. The purpose of the study was to measure the ox...

Exercise therapy has been associated with improvement in functional capacity and quality of life. The role of exercise therapy in heart transplant recipients is of great interest for the transplant society, although concerning the effect of exercise therapy, there is little knowledge at present. We analyzed the effects of exercise on alloimmune responses in murine cardiac allograft transplantat...

OBJECTIVES This study compared coronary artery calcium (CC) as detected by electron beam computed tomography (EBCT) with conventional stress testing in the evaluation of patients with symptoms suggestive of coronary artery disease (CAD). BACKGROUND Exercise electrocardiogram treadmill stress testing (treadmill-ECG) is limited by its requirement of a normal resting ECG and the ability of the p...