In this work we use transition network analysis for the first time to investigate ligand migration in truncated hemoglobin (trHbN) and obtain kinetic information about the docking-site dynamics in the protein. A comparison with explicit water molecular dynamics simulations (100 ns in total) shows that the rate constants derived from the network analysis are realistic. The transition network ana...

Cognitive function relies on a dynamic, context-sensitive balance between functional integration and segregation in the brain. Previous work has proposed that this balance is mediated by global fluctuations in neural gain by projections from ascending neuromodulatory nuclei. To test this hypothesis in silico, we studied the effects of neural gain on network dynamics in a model of large-scale ne...

Background & Aims: Suicide in developing countries is an important health problem that occurs at a young age. Our purpose in this study was to compare the suicide trends using epidemiological aspects in Hamadan province in 2006 to 2010. Materials & Methods: The mortality data of suicide for the present study was extracted from the death registry for suicide in District Health Network in Hamada...

Technology has had many influences on the Iranian society in different eras. Today, information and telecommunication technologies have revolutionized the basic structures of society and a new network society has been propagated inside the traditional and semi-modern context. In countries like Iran, which are in the process of modernization, a chaos deriving from the transition period is obs...

IPv6 has yet to become more than a worthy successor of IPv4, which remains, for now, the dominant Internet Protocol. This is due to the complicated transition period through which the Internet will have to go, until IPv6 will completely replace IPv4. One of the challenges introduced by this transition is to decide which technology is more feasible for a particular network scenario. To that end,...

A new concept of topological organization microstructures that maintain the ultrastrong coupling two-level systems to a photon field and have topology network (graph) with power-law node degree distribution has been proposed. phase transition superradiant state, which leads formation two dispersion branches polaritons is accompanied by appearance nonzero macroscopic polarization systems, studie...