نتایج جستجو برای: transfusion dependent
تعداد نتایج: 716662 فیلتر نتایج به سال:
Background: Thalassemia refers to a group of genetically inherited diseases characterized by decreased or absent synthesis normal globin chains resulting in defective chains. Most the available studies literature have been done adults and there is paucity highlighting prevalence hormonal dysfunction transfusion dependent patients pediatric age group. We conducted present study with an aim estim...
This report describes the response of eighteen DiamondBlackfan anemia (DBA) patients to recombinant human interleukin-3 (rhlL-3). rhlL-3 was administered subcutaneously once daily on an escalating dose schedule (0.5 to 10 pg/kg/d). The rhlL-3 dose was escalated every 21 days until erythroid response was attained, grade 111 or IV nonhematologic toxicity was observed, or the maximum rhlL-3 dose w...
Abstract Background Multiple transfusions in thalassemia patients may lead to antibody production against blood group antigens and hemolytic transfusion reaction might occur. In this study, antibody screening test was performed by tube and gel methods to determine the prevalence and specificity of alloantibodies in thalassemia patients. Materials and Methods In this cross-sectional study, overa...
Background: The purpose of this study was to investigate efficacy of high dose vitamin D in improving left ventricular ejection fraction (LVEF) in thalassemia patients with heart failure and vitamin D deficiency. Materials and Methods: This clinical trial study was conducted on 16 chronically transfused thalassemia patients and ventricular dysfunction with vitamin D deficiency between December...
Hepatic calcification is usually associated with infectious, vascular, or neoplastic processes in the liver. We report the first case of beta-thalassemia major with isolated diffuse hepatic calcification in a 23 year old woman, who had been transfusion-dependent since the age of 6 months. She was referred to our center with a chief complaint of abdominal pain. Computed tomography scan of the ab...
BACKGROUND Provision of safe and adequate supplies of blood is dependent on a well organised blood transfusion service with dedicated well-trained manpower and resources for the service. OBJECTIVE To provide an overview of the evolution of blood transfusion services in Kenya, from the 1980s to date. DATA SOURCES Various Government of Kenya publications and websites on blood transfusion rela...
Although acute non-haemolytic febrile or allergic reactions (ATRs) are a common complication of transfusion and often result in little or no morbidity, prompt recognition and management are essential. The serious hazards of transfusion haemovigilance organisation (SHOT) receives 30-40 reports of anaphylactic reactions each year. Other serious complications of transfusion, such as acute haemolys...
BACKGROUND Red blood cell (RBC) alloantibodies to nonself antigens may develop after transfusion or pregnancy, leading to morbidity and mortality in the form of hemolytic transfusion reactions or hemolytic disease of the newborn. A better understanding of the mechanisms of RBC alloantibody induction, or strategies to mitigate the consequences of such antibodies, may ultimately improve transfusi...
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