When rats were made tolerant to the benzodiazepine tranquilizer chlordiazepoxide (CDPX) by its steady administration, a particular g-aminobutyric acid type A (GABAA) receptor in cerebral cortex was modified. Its rate of desensitization in the absence of CDPX was enhanced (3-fold with 10 mM GABA) below saturation with GABA, and the dependence of this rate on GABA concentration was changed from s...

We present the optical and mechanical design of a mechanically compliant quasitwo-dimensional photonic crystal cavity formed from thin-film silicon in which a pair of linear nanoscale slots are used to create two coupled high-Q optical resonances. The optical cavity supermodes, whose frequencies are designed to lie in the 1500 nm wavelength band, are shown to interact strongly with mechanical r...

The majority of big data is unstructured and of this majority the largest chunk is text. While data mining techniques are well developed and standardized for structured, numerical data, the realm of unstructured data is still largely unexplored. The general focus lies on “information extraction”, which attempts to retrieve known information from text. The “Holy Grail”, however is “knowledge dis...

A theory is presented concerning the impact of attributions about the causes of emotional responses as they infl uence self-control in temptation situations. Research is reviewed indicating a high level of adult sensitivity to external infl uence in making such causal attributions. Two studies are presented in which the post transgression emotions of second-grade children are labeled shame (bec...

It has sometimes been claimed (usually without evidence) that the harm caused by an individual’s participation in a greenhouse-gas-intensive economy is negligible. Using data from several contemporary sources, this paper attempts to estimate the harm done by an average American. This estimate is crude, and further refinements are surely needed. But the upshot is that the average American is res...

The basic patterns of inheritance of learning ability in animals have been delineated. Summaries of strain differences in learning rate, responses to selective breeding for learning, heritabilities of learning phenotypes, and heterosis and overdominance are presented. In addition, the patterns of inheritance are shown to vary with the early environment. The causes of genetic differences have re...