A semantic net system in which knowled; ge is topically organized around concepts has been under development at the University of Alberta for some time. The system is capable of automatic topical classification of modal logic input sentences, concept and topic oriented retrieval, and property inheritance of a general sort. This paper presents an inference method which efficiently determines yes...

One topical challenge in knowledge engineering is to build systems that can ease the sharing and re-using of experience between a large community of users. This requires a certain plasticity of systems and associated interfaces. Yet, the lack of flexibility is a limitation of current case-based reasoning (CBR) systems. They are often developed in order to solve one particular problem and are no...

Acquired methemoglobinemia is a known complication of topical anesthesia during endoscopic procedures. Benzocaine has been implicated in a majority of cases and has been removed from some hospital formularies. However, a lot of uncertainty exists about the risk factors for this uncommon complication. This review attempts to summarize the current knowledge of this condition and describe known ri...

Learning outcomes On completion of this article you should have: • an understanding of the factors that predispose the elderly to adverse drug reactions • a detailed knowledge of ocular side effects of systemic drugs commonly prescribed to the elderly • a detailed knowledge of the side effects of topical ophthalmic drugs commonly used by elderly patients • an understanding of the importance of ...

In this paper, we first give a characterization of sub-topical functions with respect to their lower level sets and epigraph. Next, by using two different classes of elementary functions, we present a characterization of sub-topical functions with respect to their polar functions, and investigate the relation between polar functions and support sets of this class of functions. Finally, we obtai...

Confluent and Reticulate Papillomatosis (CRP) is a rare disease withpoorly recognized etiology. Various agents such as antibacterial,topical/systemic antifungal and topical/oral retinoids have beenused as treatment. Here, we report a 15-year-old female withCRP in whom yeasts of Malassezia were found in the PAS stainof the skin lesions. Topical terbinafine hydrochloride 1% sprayand oral fluconaz...

Purpose To report a case of a pediatric patient diagnosed with conjunctival lymphoma associated with oral carbamazepine use. Observation An 11-year-old boy who presented with 5-month history of a small nasal conjunctival mass in the left eye that failed therapy with topical corticosteroids. Upon excision and molecular analysis, diagnosis of Follicular Lymphoma was favored. The patient was hea...

External beam radiotherapy with high doses provokes many acute skin reactions, such as erythema and moist desquamation. Many topical preparations are used in radiation oncology departments in the skin care. Sucralfate humid gel, a colloidal physical form of the anti-ulcer drug sucralfate, promotes epithelial regeneration and activates cell proliferation. Based on this knowledge, we performed a ...

We propose a system which employs conceptual knowledge to improve topic models by removing unrelated words from the simplified topic description. We use WordNet to detect which topical words are not conceptually similar to the others and then test our assumptions against human judgment. Results obtained on two different corpora in different test conditions show that the words detected as unrela...

A 60-year-old man presented with a plaque lesion on the upper right half of the face, which had developed after ophthalmic varicella zoster infection about 2 years previously. The lesion, which was burning and itchy, included a few tiny erythematous pustules, and was slightly squamous and infiltrated. The lesion covered the upper two-thirds of the right trigeminal nerve dermatome, involving hal...