نتایج جستجو برای: tissue tropism

تعداد نتایج: 921469  

2017
Hamideh Najafi Arash Ghalyanchi Langeroudi Masoud Hashemzadeh Vahid Karimi Omid Madadgar Reza Khaltabadi Farahani Seyed Ali Ghafouri Hossein Maghsoudloo Parvaneh Seifouri Ali Madhi

Avian infectious bronchitis (IB) is a major cause of economic losses in poultry industry. The IB virus primarily affects respiratory tract, but various strains differ in their tropism for other target organs such as kidney and alimentary tract. The objective of this study was to estimate the pathogenicity of Iranian IBV variant (IR-1), which is limited exclusively to Iran. Specific pathogen fre...

Journal: :The Journal of antimicrobial chemotherapy 2012
Silvia Baroncelli Clementina Maria Galluzzo Liliana Elena Weimer Maria Franca Pirillo Anna Volpe Alessandra Mercuri Albertina Cavalli Vincenzo Fragola Laura Monno Anna Degli Antoni Nicoletta Ladisa Daniela Francisci Raffaella Bucciardini Marco Floridia

OBJECTIVES To evaluate the evolution of HIV-1 coreceptor tropism in proviral DNA of patients during maraviroc-based therapy. METHODS Fourteen heavily high active antiretroviral therapy (HAART)-treated patients with a CCR5 Trofile profile were monitored over a 24 month period from the start of maraviroc therapy. Whole-blood samples were obtained at different timepoints, and coreceptor tropism ...

Journal: :The Lancet. Infectious diseases 2011
L P R Vandekerckhove A M J Wensing R Kaiser F Brun-Vézinet B Clotet A De Luca S Dressler F Garcia A M Geretti T Klimkait K Korn B Masquelier C F Perno J M Schapiro V Soriano A Sönnerborg A-M Vandamme C Verhofstede H Walter M Zazzi C A B Boucher

Viral tropism is the ability of viruses to enter and infect specific host cells and is based on the ability of viruses to bind to receptors on those cells. Testing for HIV tropism is recommended before prescribing a chemokine receptor blocker. In most European countries, HIV tropism is identified with tropism phenotype testing. New data support genotype analysis of the HIV third hypervariable l...

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