OBJECTIVES The objective of this study is to develop an experimental model of hyperlipidemia and insulin resistance (IR), markers of coronary heart disease (CHD) using high fat and high sugar (HFHS) diet and to evaluate the efficacy of the model using atorvastatin, a known antihyperlipidemic drug, pioglitazone, a known insulin sensitizer, and Tinospora cordifolia (Tc), an antidiabetic plant. ...

Objectives: The present study undertaken to explore antioxidant and the cell line of isolated compound from ethanol extract Tinospora cordifolia belongs family Menispermaceae.
 Methods: air dried powdered sample aerial parts T. was extracted in a Soxhlet using five different solvents. Most active extracts were purified silica gel column chromatography. Characterized structure Fourier trans...

Background: Tinospora cordifolia has gained popularity as an immunomodulatory and protective herb. Being anIndian traditional herb, it found its use in Ayurveda alternative system of medicine. According to World Health Organization, still 80% the world population relies on therapies for disease infirmity. Dearth medicine treatment COVID-19 pushed researcher towards therapies. This review focuse...

India has a vast range of medicinal plants at its disposal. Tinospora cordifolia, often known as "Seenthil Kodi" , is dioecious hanging shrub, proven to be valuable botanical for herbal medicine, with an extensive array bioactive components. The goal the current research was determine ideal lines high stem yield and also assess genetic diversity, heritability, advance trait association in crop....

The inevitable development of chemoresistance and unmanageable side effects are the major therapeutic challenges in management of breast cancer imposing an urgent need for identification of novel therapeutic agents. In the present investigation, we report anti-proliferative activity of chloroform fraction of Tinospora cordifolia (TcCF), an Ayurvedic medicinal plant, on breast cancer cells. We f...

A preparation of Tinospora cordifolia (RTc) administered i.p. (200 mg/kg b.w.) to strain "A" male mice 1 h before whole body gamma-irradiation was evaluated for its radioprotective efficacy in terms of whole body survival, spleen colony forming units (CFU), hematological parameters, cell cycle progression, and micronuclei induction. Preirradiation treatment with RTc rendered 76.3% survival (30 ...